Perhaps the most subtle source of invalidity in behavioral research is the elusive phenomenon of regression.Even seasoned researchers have frequently failed to detect its presence; hence, it has spoiled many otherwise good research efforts. Studies of atypical and special groups have probably been the victims of the regression phenomenon more often than those in any other single area of inquiry. A simple statistical truism is that when subjects are selected because they deviate from the mean on some variable, regression will always occur.Many studies on remediation and treatment of the handicapped and other deviant groups follow this pattern : those in greatest &dquo;need&dquo; are selected, a treatment is administered, and a reassessment then follows. For example, suppose all children having IQ scores below 80 were given some special treatment (e.g., glutamic acid) over a period of a year and were then retested. Assume that the time interval, etc., between testing.s was such that there was no practice or carryover effect. If the treatment had absolutely no effect, how would the experimental group fare on the posttest? Assume a