Problems encountered in tympanoplastic surgery

Brockman, Seymour J.

doi:10.1288/00005537-196107000-00014

Cited by 17 publications

(9 citation statements)

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“…These studies have confirmed that the predominant feature in the histological picture is a submucous formation of collagenous connective tissue, poor in cells, followed by hyaline degeneration (Brockmann, 1961 ;House & Sheehy, 1960;Joseph & Gordon, 1963;Igarashi et al, 1970).…”

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confidence: 78%

Histology of Tympanosclerosis

Sørensen

1972

Acta Oto-Laryngologica

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Light-and electronmicroscopic studies of tissue from pithological middle ears revealed in sixteen cases changes typical of tympanosclerosis, i.e. collagenous connective tissue poor in cells, with hyaline degeneration and occasional calcium deposits. In one case new formed cartilaginous tissue was present. In several specimens we found granulation tissue, which is assumed to represent the incipient stage in the pathogenesis of tympanosclerosis. Electronmicroscopy has revealed that ths degenerative process involves not only connective tissue, but also the epidermis of the tympanum. It is stressed that the diagnosis of tympanosclerosis can be established only by means of microscopic study of the removed tisrue.

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confidence: 78%

Histology of Tympanosclerosis

Sørensen

1972

Acta Oto-Laryngologica

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“…It is a pathological process that is quite prevalent in our country because it is frequently detected in acute infections, especially chronic ME mucosa infections 1,9 . Despite the fact that they had been well defined in their histological characteristics 1,[4][5][6][7][8] , etiology and pathogenesis are not completely explained and better understanding of these aspects may bring future possibilities of preventive treatment.…”

Section: Discussionmentioning

confidence: 99%

“…It is defined in the literature as hyaline degeneration that occurs in the collagen matrix that is formed during the repairing process, which can deposit calcium and phosphorus crystals. 1,[5][6][7] However, these deposits are not always present and the tympanosclerotic process may be characterized basically by hyalinization of neoformed collagen tissue of lamina propria and we considered as positive for myringosclerosis if there were phases 4 or 5 of the studied tissue.…”

Section: Discussionmentioning

confidence: 99%

“…It is the final stage of a process originated from acute, chronic or recurrent inflammation of ME lamina propria, characterized by progressive infiltrate of fibroblasts, causing an increase in collagen, which originates poor formation of cells and blood vessels, followed by hyaline degeneration and in some occasions, calcium deposit 1,[4][5][6][7] , which may lead to formation of cartilage or bone 8 . In some cases there may be functional damage for the tympanic-ossicle unit, causing conductive hearing loss, which affects surgical decisions during tympanoplasties.…”

Section: Introductionmentioning

confidence: 99%

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Achados otomicroscópicos e histológicos da miringoesclerose induzida em ratos: estudo crítico de um modelo experimental

Santos

Gouveia

Peixoto

et al. 2005

Rev. Bras. Otorrinolaringol.

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Myri ngosclerosis is characterized by hyaline changes of the lamina propria of the tympanic membrane. Experimental studies have used otomicroscopy or histology to evaluate myringosclerosis in animals, but they do not correlate precisely these two methods. Aim: The present study evaluates the accuracy of otomicroscopy in the diagnosis of myringosclerosis in rats. Study design: experimental. Material and Method: Myringosclerosis was induced by transtympanic inoculation of Streptococcus pneumoniae in 25 Wistar rats, which were examined weekly through otomicroscopy and sacrificed after eight weeks for histologic study of their tympanic membranes. Results: From the comparison of the otomicroscopic data in relation to the histologic findings, we could observe sensibility of 80% and specificity of 75% for the otomicroscopy. Conclusion: Considering the results in this study, otomicroscopy did not represent a good method to evaluate myringosclerosis in this experimental model.

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“…Therefore, he again resorted to the type IV procedure. 7 The discussion of that he had observed poor results in the use of PE struts for converting type IV into type III cases. It was his suggestion that foreign materials should not be used in in¬ fected ears.…”

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confidence: 99%