Problèmes posés par la prescription des tétracyclines durant les premières années de vie

Brosset, A.; Nouaille, Y.; Merle, Louis

doi:10.1016/s0248-8663(87)80177-7

Cited by 4 publications

(4 citation statements)

References 34 publications

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“…32 Because tetracycline seems to be problematic mostly in growing bones and teeth, tissues already mineralized should not be affected and should not become fluorescent green when exposed to tetracycline, unless new mineralization occurs. 19 Because significantly discolored teeth were not noted in any of our patients, tetracycline exposure must have occurred when they were older than 8 to 10 years (after mineralization of teeth). In fact, all of the patients were exposed only during adolescence.…”

Section: Tetracyclinementioning

confidence: 80%

“…16,17 Tetracyclines are therefore active against gram-positive and gram-negative bacilli, enterobacteriaceae, chlamydia, spirochetes, mycoplasma, rickettsia, actinomyces, atypical mycobacteria, and amoebae. [17][18][19] They are often used for prolonged periods in the treatment of acne. 15,18 Some of the most frequent side effects encountered with tetracyclines include gastrointestinal irritation with abdominal discomfort, nausea, and vomiting.…”

Section: Tetracyclinementioning

confidence: 99%

“…17 Children are at risk of discoloration of permanent teeth up to the age of 8 to 12 years. 16,18,19,22,23 Tetracycline is therefore generally contraindicated during these time periods. Notably, there have been reports that staining can occur when tetracyclines are given during long periods of time in adulthood because of continued demineralization and remineralization of the enamel or dentine.…”

Section: Tetracyclinementioning

confidence: 99%

“…16,19,20 Whether or not enamel and dentine hypoplasia or hypomineralization can result from tetracycline exposure is debatable. 16,17,19,27 Interestingly, fingernails and toenails are also at risk of blackish discoloration and onycholysis from the use of tetracycline, especially after exposure to the sun. 28,29 Unlike teeth that are fully calcified at the end of childhood, nails can be affected into adulthood because they maintain an active state of growth.…”

Section: Tetracyclinementioning

confidence: 99%

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Green Bone

Boulos¹

2007

Arch Ophthalmol

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Todescribetheunusualfindingofyellow-greencolored bone during routine orbital surgery, to detail its investigation, and to demonstrate its benign nature. Methods: When green bone was found, specimens were sent for light and fluorescent microscopy, ultraviolet photography, and spectrophotometry. Results: Yellow-green bone was encountered in 3 patients during orbital tumor excision or orbital fracture repair procedures. The only common cause was prior use of tetracycline during adolescence. All patients had healthy white dentition. In all cases, absence of neoplasia was demonstrated histologically. The bone fluoresced with a bright yellow-green color when exposed to 365-nm ultraviolet light. Histologic analysis demonstrated fluorescence located near the haversian canals. Spectrophotometry revealed absorption at 4 wavelengths specific to tetracycline: 230, 275, 380, and 440 nm. Conclusions: Fixation of tetracycline and ensuing fluorescence occurs mostly in areas of new bone growth and mineralization. This happens during childhood but also with bone remodeling associated with tumors or fractures. Once mineralized, teeth should therefore not be affected if tetracycline exposure occurs after ages 8 to 10 years. This paucity of external clues can lead to the surprising but innocuous surgical finding of green bone. Careful history and proper investigation can confirm its origin.

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Section: Tetracyclinementioning

confidence: 80%

Section: Tetracyclinementioning

confidence: 99%

Section: Tetracyclinementioning

confidence: 99%

Section: Tetracyclinementioning

confidence: 99%

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Green Bone

Boulos¹

2007

Arch Ophthalmol

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Tailor-made biochar-based nanocomposite for enhancing aqueous phase antibiotic removal

Shaikh,

Chakraborty,

Kumar

et al. 2023

Journal of Water Process Engineering

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Campylobacter jejuni subdural hygroma infection in a 2-year old boy: case report and a brief literature review

et al. 2022

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Background Campylobacter jejuni is a common cause of acute gastroenteritis, but central nervous system infections are rare manifestations of Campylobacter infection. Therefore, C. jejuni trauma-related subdural hygroma infection in children is poorly described in the literature. Case presentation We described a 2-year old boy with lobar holoprosencephaly presenting with subdural hygroma following head trauma. C. jejuni infection was confirmed from a subdural hygroma sample by culture as well as by DNA sequencing of a broad range 16S rDNA PCR product. Cerebrospinal fluid from the ventriculoperitoneal shunt remained sterile. Combined neurosurgical and antimicrobial treatment led to complete recovery. Review of the literature showed that the most common manifestation of Campylobacter central nervous system infection is meningitis, mostly in neonates, and subdural hygroma infection was described for only one case. Conclusions Subdural hygroma infection caused by C. jejuni is a rare clinical condition in children. Molecular methods represent an important tool for the detection of rare or unexpected pathogens. No standard recommendations for antimicrobial treatment of C. jejuni subdural space infection in children are available, but meropenem treatment combined with surgery seems to be an effective approach.

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Problèmes posés par la prescription des tétracyclines durant les premières années de vie

Cited by 4 publications

References 34 publications

Green Bone

Green Bone

Tailor-made biochar-based nanocomposite for enhancing aqueous phase antibiotic removal

Campylobacter jejuni subdural hygroma infection in a 2-year old boy: case report and a brief literature review

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