Probiotics in the prevention of antibiotic-associated diarrhea in children: A meta-analysis of randomized controlled trials

Role of Probiotics in Prevention and Treatment of Antibiotic-Associated Diarrhea in Children

“…Сохранение и коррекция микроэкологии кишечника тре-бует назначение пробиотиков, цитомукопротекторов, метаболитов бактерий-симбионтов и продуктов функ-ционального питания на основе молочнокислых бактерий и др. [31][32][33][34][35].…”

Probiotics and health: An evidence-based review

“…Most antibiotics may induce, during their use, diarrhea: the risk is greater in case of aminopenicillin therapies, aminopenicillin combined with clavulanic acid, cephalosporins, and clindamycin [65]. Recent meta-analyses reported a significant reduction of AAD cases when antibiotic therapy is associated with prior probiotic treatment [65][66][67]. Saccharomyces boulardii appears to be the most effective microorganism; however, LGG has also proven to be effective in children [68,69].…”

The developing intestinal microbiome and its relationship to health and disease in the neonate

“…46,47 For example, not all probiotics have the same effect when treating acute infectious diarrhea, inflammatory bowel disease or antibiotic-associated diarrhea. 48 Probiotics that have shown some beneficial effects are Lactobacillus sp and Bifidobacterium sp, both commonly found in higher proportion in the intestinal microbiota of breast-fed infants compared with formula-fed infants. Probiotics in part are thought to exert their effect by modulating the intestinal microflora, reducing intestinal permeability and decreasing proinflammatory cytokines and increasing anti-inflammatory cytokines.…”