Probiotics: Helpful for the prevention of COVID-19?

Abstract

Up to now, no vaccine has been developed for COVID-19 treatment. Although many scientists are working for the rapid development of a vaccine to control this pandemic, nonetheless, it will take time. If the vaccine will be developed soon, it will not be available to the entire world instantly since the mass production of the vaccine will take time. In this scenario, we will have to take alternative measures to control the COVID-19 pandemic. These alternative approaches include the stimulation of the immune system to fight against viral infections. Among the different approaches to strengthen the immune system, the use of probiotics is the best one. Probiotics can help the body to fight against COVID-19 directly and indirectly. In this review, we comprehensively discuss the use of probiotics for the prevention and control of COVID-19.

Role of Probiotic for Prevention and Management of COVID-19: A Literature Review

“…Besides, there was a randomized, twofold dazed fake treatment controlled examination with 523 young people who were given L. gasseri PA 16/8, Bifidobacterium longum SP 07/3, and B. bifidum MF 20/5, for certain minerals and nutrients. The outcomes showed lower influenza periods and a decrease in fever days [18].…”

“…The new investigation of Ji et al showed that the supplementation of probiotics to respiratory syncytial virus-contaminated mice has essentially raised the bounty of short-chain unsaturated fat (SCFA) delivering gut microbiota which thusly up-direct the creation of IFN-β. Furthermore, they have additionally revealed the upsurge of Corynebacterium and Lactobacillus species in the lung due to higher SCFA creation, subsequently prompting the actuation of interferon β creation in alveolar macrophages [18].…”

“…In addition, patients are likewise as of now influenced by auxiliary bacterial contaminations [25]. An earlier report showed that mice with aspiratory disease because of Pseudomonas aeruginosa and S. aureus, when orally controlled with probiotic strains of L. acidophilus, exhibited a decline in the bacterial weight from the lungs and a decrease in the odds of lung disability and foundational contaminations [18].…”

“…Lastly, probiotics stimulate the differentiation of plasma cells systemically to produce immunoglobulin A [18] Diet, Probiotic, and COVID-19…”

Current Updates on Therapeutic and Vaccine Approaches for Covid-19 Disease

“…Paracasei, L mesenteroides (Lehtoranta et al, 2014;Zelaya et al 2016) . These probiotics are involved in reducing the occurrence and severity of respiratory tract infection, as well as in boosting the immune system of the body (Zafar et al 2020). A study to determine beneficial effect of Lactobacillus coryniformis K8 along with dietary supplements to protect healthcare workers from contracting COVID-19 was carried out and has been registered at ClinicalTrials.gov (NCT04366180) (Tahir et al 2020).…”