Probiotics for Treatment and Prevention of Urogenital Infections in Women: A Systematic Review

Abstract

The quality of the studies in this systematic review varied. Although clinical practice recommendations were limited by the strength of evidence, probiotic interventions were effective in treatment and prevention of urogenital infections as alternatives or co-treatments. More good quality research is needed to strengthen the body of evidence needed for application by clinicians.

Health problems associated with irritable bowel syndrome: analysis of a primary care registry

“…There may thus be a pathophysiological link between IBS and urogenital infections. Future studies are needed to unravel such a link and its mechanisms (eg microbiota, immune system, anatomical proximity), which go beyond the scope of the present study.…”

Probióticos: haverá algum benefício no tratamento e prevenção das infeções urogenitais na mulher adulta?

“…A pertinência deste tema justifica-se, não só pela frequência das infeções urogenitais estudadas e suas consequências na saúde da mulher, como também pelo interesse crescente da comunidade científica e população acerca da utilização de probióticos. [1][2] Relativamente à qualidade metodológica desta revisão considera-se que não existem falhas graves. Foram seguidas orientações internacionais validadas na sua realização; no entanto, a abrangência dos critérios de inclusão poderá ter contribuído para a heterogeneidade dos estudos avaliados.…”

In vitro characterization of Lactobacillus crispatus IP174178 and its live biotherapeutic product for prevention of vaginal infections

“…Vulvovaginal candidiasis (VVC), bacterial vaginosis (BV), and urinary tract infection (UTI) are the most common urogenital pathologies. These pathologies negatively impact women's quality of life and represent a significant healthcare cost [18,19]. Lactobacillus spp., and in particular L. crispatus, are commonly used as probiotics to prevent the development of pathogens, including those responsible for VVC and BV [20,21].…”