Probiotic increase the antirabies humoral immune response in bovine

Arenas, Sandro Eduardo; Reis, L. S. L. S.; Frazatti-Gallina, N. M.; Fujimura, Shiro; Bremer‐Neto, Hermann; Pardo, Paulo Eduardo

doi:10.4321/s0004-05922009000400011

Cited by 4 publications

(6 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…According to Albas et al (2005), immunity does not persist for more than 30 days after the first vaccination; however, in the G8P group, the percentage of animals with titers considered protective was sustained ( Figure 1). This result indicates that the supplementation caused a persistent immune stimulation effect (MUSA et al, 2009), which was also described by Arenas et al (2009), who used similar microorganisms and doses, although the probiotics added were enzymes and zinc. According to Maria et al (2009), zinc has an immunomodulatory role, which may have interfered beneficially in that study.…”

Section: Harvest (Days)supporting

confidence: 55%

“…The bacteria in question potentiate vaccines via modulatory influences on the immune response such as increasing the production of antibodies and activating macrophages, T-cell proliferation and interferon production (ROOS, 2006). In addition, these results demonstrate that increases in the concentration of associated probiotic microorganisms in the mineral mixture enhance the beneficial immunomodulatory effects of the probiotic, which was also described by Arenas et al (2009). Table 2.…”

Section: Frequency Of Cattle With Titers Of Antirabies Antibodiessupporting

confidence: 50%

“…It included 30 days for the animals to adapt to the rotational grazing system and establish a consumption rate of 70 g/animal/day of mineral mixture plus added concentrations of probiotics (ARENAS et al, 2007). This was followed by a 60-day trial period that was conducted on a farm in the district of Pirapozinho, SP, Brazil.…”

Section: Methodsmentioning

confidence: 99%

“…It has become necessary to find alternative ways to increase the effectiveness of vaccination against rabies (FERREIRA et al, 2009), one of which, according to Arenas et al (2007), could be the use of probiotic food components (GENARO et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Efeito da concentração de bactérias probióticas como imunomodulador da produção de anticorpos antirrábicos em bovinos vacinados

et al. 2016

View full text Add to dashboard Cite

This study evaluated the effects of supplementation with a combination of probiotic microorganisms, added at different concentrations to the mineral mixture, on the production of serum antibodies against rabies virus in cattle vaccinated with a single dose of rabies vaccine. Forty-two male Nellore cattle, aged 12 months, were randomly divided into three groups (n = 14): the control group (CG) received 70 grams of mineral mixture/animal/day; and the 2 gram probiotic group (G2P) and 8 gram probiotic group (G8P) received 70 grams of mineral mix/animal/day with 2 and 8 grams added, respectively, of a combination of probiotic microorganisms (Lactobacillus acidophilus, Streptococcus faecium, Bifidobacterium thermophilum and Bifidobacterium longum). Individual antibody titers were determined using a neutralization in cell-based rapid fluorescent focus inhibition test (RFFIT) technique. One-way analysis of variance (one-way ANOVA) was used with contrasts using the Tukey method to determine whether the experimental groups differed within each time point, and the paired t-test was used to determine whether differences occurred between time points within each group. The level of significance was set at 5%. There were statistically significant differences between the mean serum concentrations of the CG and G8P groups at 30 and 60 days after the first vaccination, and at 60 days, 100% of the animals maintained minimum titers of protective antibodies only in the G8P group. There was also improvement in the production of antibodies in the G2P group compared with the CG after 30 and 60 days, but this difference was not statistically significant. In conclusion, increasing doses of probiotic added to the mineral mix beneficially affected the rabies humoral immune response, as determined by serum antibodies, and enabled the maintenance of minimum protective titers for a longer period in previously vaccinated cattle. ResumoEsse estudo avaliou o efeito da suplementação de uma associação de microrganismos probióticos, adicionados à mistura mineral em diferentes doses, na produção de anticorpos séricos antirrábicos em bovinos primovacinados. Quarenta e dois bovinos Nelore machos, com idade de 12 meses, foram divididos em três grupos (n=14): grupo controle (GC) recebeu 70 gramas de mistura mineral/animal/dia; grupos probiótico 2 gramas (G2P) e 8 gramas (G8P) receberam 70 gramas de mistura mineral/animal/dia adicionados respectivamente de 2 e 8 gramas de probióticos (Lactobacillus acidophilus, Streptococcus faecium, Bifidobacterium thermophilum e Bifidobacterium longum). Os títulos individuais de anticorpos antirrábicos foram determinados por meio da técnica de soroneutralização em células baseado no rapid fluorescent focus inhibition test (RFFIT). Os resultados obtidos foram comparados pelo teste t não pareado, com 5% de nível de significância. Houve diferenças estatísticas significativas entre as médias de concentrações séricas entre os grupos GC e G8P, após 30 e 60 dias da primovacinação e após 60 dias, somente o G8P manteve...

show abstract

Section: Harvest (Days)supporting

confidence: 55%

Section: Frequency Of Cattle With Titers Of Antirabies Antibodiessupporting

confidence: 50%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Efeito da concentração de bactérias probióticas como imunomodulador da produção de anticorpos antirrábicos em bovinos vacinados

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Houve uma redução das médias (e desvios padrão) dos títulos de anticorpos soroneutralizantes contra o vírus rábico cepa vírus Pasteur, entre os dias 30 e os 60 dias, em todos os grupos estudados, porém, no grupo probiótico, esta redução foi mais acentuada (2,853±3,336) do que nos grupos controle (2,593± 2,603) e Probiótico + Zinco (1,244± 0,643). Este resultado pode ser explicado porque para este estudo ser realizado, foi utilizado como referência um trabalho feito por Arenas et al (2009) Na primeira coluna (30 dias), os animais dos grupos em estudo obtiveram total proteção contra raiva (100%), com títulos soroneutralizantes>0,5UI/ mL. Na coluna seguinte (60 dias), o GP e GPZn apresentaram valores iguais na redução de animais protegidos (13,4%), porém o GC reduziu em 46,7% na proteção de animais protegidos contra o vírus rábico, possivelmente porque o GC não possuía nenhum suplemento nutricional ligado ao estímulo do sistema imunológico.…”

Section: Grupounclassified