Probiotic: An Uprising Human Health Concept

Bhatt, Amishi; Kothari, D.P.; Kothari, Charmy; Kothari, Ramesh

doi:10.5772/intechopen.98828

Cited by 2 publications

(1 citation statement)

References 83 publications

(87 reference statements)

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“…The gut microbiota creates a hostile habitat for pathogens, produces antimicrobial compounds, and boosts the human body's defences. It also promotes peristalsis, which causes the contents of the gut to flow more swiftly, making it more difficult for infections to establish themselves [59].…”

Section: Manymentioning

confidence: 99%

Substrates and Metabolic Pathways in Symbiotic Culture of Bacteria and Yeast (Scoby) Fermentation: A Mini Review

Zailani

Adnan²

2022

Jurnal Teknologi

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Kombucha is a fermented beverage that is prepared traditionally by fermenting Symbiotic Culture of Bacteria and Yeast (SCOBY) with sugar and black/green tea, which is known as Camellia sinensis leaves. The previous study analyses the microbial composition that can be obtained in Kombucha production. Study shows that yeast species and acetic acid bacteria (AAB) species are the microorganisms that involve in the fermentation process of Kombucha. Some studies emphasize the chemical composition that was obtained from the production of Kombucha drinks such as organic acids, sugars, ethanol, and polyphenols. However, further review and elucidation regarding the substrates used and metabolic activity in Kombucha fermentation is necessary. Thus, the objective of this study is to review the metabolic pathway and substrates involve in Symbiotic Culture of Bacteria and Yeast (SCOBY) fermentation. This review also collected information related to the symbiosis of fermentation by yeast and AAB pathway in Kombucha fermentation. Several pharmaceutical effects of Kombucha were also discussed to prove the health benefits of Kombucha. To produce good quality and high yield of Kombucha that can provide various health benefits to consumers, it is crucial to understand the connection between the metabolic activity with Symbiotic Culture of Bacteria and Yeast (SCOBY) during the fermentation process of Kombucha. By conducting this review work, it could provide an insightful overview and better understanding of metabolic pathways and substrates involved in SCOBY and Kombucha fermentation.

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Section: Manymentioning

confidence: 99%

Substrates and Metabolic Pathways in Symbiotic Culture of Bacteria and Yeast (Scoby) Fermentation: A Mini Review

Zailani

Adnan²

2022

Jurnal Teknologi

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Recent updates on correlation between reactive oxygen species and synbiotics for effective management of ulcerative colitis

Ashique¹,

Mishra

Garg

et al. 2023

Front. Nutr.

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Ulcerative colitis (UC) is presently considered a multifactorial pathology, which may lead to persistent inflammatory action of the gastrointestinal tract (GIT) because of an improperly managed immunological reactivity to the intestinal microbiota found in the GIT. The immune response to common commensal microbes plays an essential role in intestinal inflammation related to UC synbiotics, and it is an important element in the optimal therapy of UC. Therefore, synbiotics, i.e., a mixture of prebiotics and probiotics, may help control the diseased state. Synbiotics alleviate the inflammation of the colon by lowering the reactive oxygen species (ROS) and improving the level of antioxidant enzymes such as catalase (CAT), glutathione peroxidase (GPX), and superoxide dismutase (SOD). Prebiotic supplementation is not a common practice at the moment, despite numerous research findings proving that the benefits of both probiotics and prebiotics encourage their continued existence and positioning in the GIT, with positive effects on human health by managing the inflammatory response. However, the fact that there have been fewer studies on the treatment of UC with different probiotics coupled with selected prebiotics, i.e., synbiotics, and the outcomes of these studies have been very favorable. This evidence-based study explores the possible role of ROS, SOD, and synbiotics in managing the UC. The proposed review also focuses on the role of alteration of gut microbiota, antioxidant defense in the gastrointestinal tract, and the management of UC. Thus, the current article emphasizes oxidative stress signaling in the GI tract, oxidative stress-based pathomechanisms in UC patients, and UC therapies inhibiting oxidative stress’ effects.

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Probiotic: An Uprising Human Health Concept

Cited by 2 publications

References 83 publications

Substrates and Metabolic Pathways in Symbiotic Culture of Bacteria and Yeast (Scoby) Fermentation: A Mini Review

Substrates and Metabolic Pathways in Symbiotic Culture of Bacteria and Yeast (Scoby) Fermentation: A Mini Review

Recent updates on correlation between reactive oxygen species and synbiotics for effective management of ulcerative colitis

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