Probing the metalloproteome: an 8-mercaptoquinoline motif enriches minichromosome maintenance complex components as significant metalloprotein targets in live cells

McKenna, Sean M.; Florea, Bogdan I.; Zisterer, Daniela M.; van Kasteren, Sander I.; McGouran, Joanna F.

doi:10.1039/d4cb00053f

RSC Chem. Biol.

2024

DOI: 10.1039/d4cb00053f

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Probing the metalloproteome: an 8-mercaptoquinoline motif enriches minichromosome maintenance complex components as significant metalloprotein targets in live cells

Sean M. McKenna,

Bogdan I. Florea,

Daniela M. Zisterer

et al.

Abstract: A mercaptoquinoline based photo affinity probe for profiling metalloproteins was developed and applied in live cell assays, identifying several novel, therapeutically significant protein targets.

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Probing the metalloproteome: an 8-mercaptoquinoline motif enriches minichromosome maintenance complex components as significant metalloprotein targets in live cells

Abstract: A mercaptoquinoline based photo affinity probe for profiling metalloproteins was developed and applied in live cell assays, identifying several novel, therapeutically significant protein targets.

Cited by 0 publications

References 67 publications

No citations

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