“…The roles of sPLAzs in signal transduction and inflammatory processes have been extensively investigated (for reviews from 1990 onward, see [26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45]. Previous reviews on the in vitro properties of purified sPLAzs include those on structure/function (9,21,25,27,(46)(47)(48)(49), interfacial recognition (50, 51), interfacial kinetics (4, 18, 52-56), and inhibition (32,(57)(58)(59)(60)(61). Elements of these reviews, structural studies, and more recent data that relate to the fu n-damental concepts of interfacial catalysis described in the first part of the present review are summarized in this section.…”