Probing biomechanical properties with a centrifugal force quartz crystal microbalance

Webster, Aaron; Vollmer, Frank; Sato, Yuki

doi:10.1038/ncomms6284

Cited by 28 publications

(13 citation statements)

References 49 publications

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“…As shown in the inset of Fig. 3, we estimate that the divergence takes place at R/δ ∼ 3, which is consistent with the experimental data by Sato et al [59] with micron-sized particles, at the other side of the divergence.…”

Section: Comparison With Experimentssupporting

confidence: 92%

Quantitative reintepretation of quartz-crystal-microbalance experiments with adsorbed particles using analytical hydrodynamics

Schofield,

Buscalioni

2020

Preprint

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Despite being a fundamental tool in soft matter research, quartz crystal microbalance (QCM) analyses of discrete macromolecules in liquid so far lack a firm theoretical basis. Currently, acoustic signals are qualitatively interpreted using ad-hoc frameworks based on effective electrical circuits, effective springs and trapped-solvent models with abundant fitting parameters. Nevertheless, due to its extreme sensitivity, the QCM technique pledges to become an accurate predictive tool. Using unsteady low Reynolds hydrodynamics we derive analytical expressions for the acoustic impedance of adsorbed discrete spheres. Our theory is successfully validated against 3D simulations and a plethora of experimental results covering more than a decade of research on proteins, viruses, liposomes, massive nanoparticles, with sizes ranging from few to hundreds of nanometers. The excellent agreement without fitting constants clearly indicates that the acoustic response is dominated by the hydrodynamic impedance, thus, deciphering the secondary contribution of physico-chemical forces will first require a hydrodynamic-reinterpretation of QCM.

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Section: Comparison With Experimentssupporting

confidence: 92%

Quantitative reintepretation of quartz-crystal-microbalance experiments with adsorbed particles using analytical hydrodynamics

Schofield,

Buscalioni

2020

Preprint

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“…Both the spheres and the resonator surface carried negative charge, resulting in an electrostatic repulsion, which competes with the attractive forces. Variation of ion strength as indicated in the legend tuned this repulsive force [ 168 ]. Adding salt has two consequences.…”

Section: Coupled Resonancesmentioning

confidence: 99%

Studying Soft Interfaces with Shear Waves: Principles and Applications of the Quartz Crystal Microbalance (QCM)

Johannsmann

Langhoff

Leppin

2021

Sensors

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The response of the quartz crystal microbalance (QCM, also: QCM-D for “QCM with Dissipation monitoring”) to loading with a diverse set of samples is reviewed in a consistent frame. After a brief introduction to the advanced QCMs, the governing equation (the small-load approximation) is derived. Planar films and adsorbates are modeled based on the acoustic multilayer formalism. In liquid environments, viscoelastic spectroscopy and high-frequency rheology are possible, even on layers with a thickness in the monolayer range. For particulate samples, the contact stiffness can be derived. Because the stress at the contact is large, the force is not always proportional to the displacement. Nonlinear effects are observed, leading to a dependence of the resonance frequency and the resonance bandwidth on the amplitude of oscillation. Partial slip, in particular, can be studied in detail. Advanced topics include structured samples and the extension of the small-load approximation to its tensorial version.

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“…Extensive research has been done on various types of tubes containing fluid flow, but most of this research has been limited to linear models and a small number of variable cross-sections. Probing biomechanical properties with a centrifugal force quartz crystal microbalance [1]. This study examines flexible tubes containing flow.…”

Section: Introductionmentioning

confidence: 99%

Nonlinear vibration and dynamic response of nano composite conical tube by conveying fluid flow

Rahmani

Petrudi

2020

International Advanced Researches and Engineering Journal

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Modeling of tubes containing fluid flow is widely used in the study of heat exchangers, nuclear reactors, micro and nano tools, etc. This system is structurally simple but very complex in terms of dynamic behavior and vibrations. In this paper, an analytical relationship for nonlinear vibrations of self-excitation of a nanocomposite conical tube containing fluid flow is extracted, one end of which is free and the other side is fixed and is under gravitational force. The base material is assumed to be 1200 series aluminum, which is reinforced with carbon nanotubes. The Hamiltonian equations are obtained, assuming the Euler-Bernoulli beam theory and the use of the Galerkin method, dissected the partial derivative equations into Ordinary Differential Equations (ODE), then solved by MATLAB coding and investigated the effect of various parameters on system behavior. As the fluid velocity increases, the amplitude of the vibration increases and the nonlinear effects of the system increase, so more modes are needed to converge the responses. In a conical tube, the βT coefficient increases with increasing inner diameter along the tube and the system becomes more stable. Increasing the length of the pipe makes the opening conical pipe more stable and the closing conical pipe more unstable. The change in length has no effect on the stability of the cylindrical tube.

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Probing biomechanical properties with a centrifugal force quartz crystal microbalance

Cited by 28 publications

References 49 publications

Quantitative reintepretation of quartz-crystal-microbalance experiments with adsorbed particles using analytical hydrodynamics

Quantitative reintepretation of quartz-crystal-microbalance experiments with adsorbed particles using analytical hydrodynamics

Studying Soft Interfaces with Shear Waves: Principles and Applications of the Quartz Crystal Microbalance (QCM)

Nonlinear vibration and dynamic response of nano composite conical tube by conveying fluid flow

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