Probing Allosteric Relationships Between the Neurotransmitter-Binding Site and the Binding Pocket of the Anthelmintic Drug Ivermectin in Glutamate-Gated Chloride Channels

Abstract

Receptors belonging to the Cys-loop gene superfamily of neurotransmittergated ion channels (e.g. acetylcholine, serotonin, GABA, and glycine recep-