Probenecid Inhibits Influenza A(H5N1) and A(H7N9) Viruses In Vitro and in Mice
Jackelyn Murray,
David E. Martin,
Sarah Hosking
et al.
Abstract:Avian influenza (AI) viruses cause infection in birds and humans. Several H5N1 and H7N9 variants are highly pathogenic avian influenza (HPAI) viruses. H5N1 is a highly infectious bird virus infecting primarily poultry, but unlike other AIs, H5N1 also infects mammals and transmits to humans with a case fatality rate above 40%. Similarly, H7N9 can infect humans, with a case fatality rate of over 40%. Since 1996, there have been several HPAI outbreaks affecting humans, emphasizing the need for safe and effective … Show more
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