“…The predominant ancestry is reported to be from the United Kingdom and Europe (51–81 %)[ 42 ] and, therefore the clinical presentation and pedigree of CADASIL is hypothesized to be most similar to individuals from those regions [ 9 , 43 ]. However, there is also a growing Asian and South East Asian population [ 42 ], which may influence the range of clinical presentation of CADASIL[ 44 , 45 ] in Australia. This multi-ethnic distribution adds to the novelty of AusCADASIL in bringing together individuals from these previously studied regions.…”