Pro‐healing effect of Cinnamomum zeylanicum bark

Abstract

The ethanol extract of the bark of Cinnamomum zeylanicum was evaluated for wound healing activity in Wistar rats. The extract was administered by the oral route at a dose of 250 mg/kg and 500 mg/kg body weight (1/8 and 1/4 of LD(50), respectively) for all the wound models selected, excision, incision and dead space wounds. The extract significantly enhanced the wound breaking strength in the case of incision wound, the rate of wound contraction and the period of epithelization in the case of excision wound. The granulation tissue weight, its breaking strength and its hydroxyproline content was also increased by the extract in the dead space wound.

Wound healing activity of Cleome rutidosperma DC. roots

“…The rats were inflicted with excision wounds as described by Morton and Malone (1972) and suggested by Kamath et al (2003). An impression was made on the dorsal thoracic region 1cm away from vertebral column and 5cm away from ear on the anaesthetized rat.…”

Immunomodulatory activity ofCinnamomum zeylanicumbark

“…Apart from its use as spice, it is shown to possess a wide range of pharmacological effects such as antidiabetic (Khan et al, 2003), hypolipidemic (Kamath et al, 2003;Usta et al, 2003), antibacterial (Nir et al, 2000), and antifungal activities (Ranasinghe et al, 2002). Further, it is widely believed in India that cinnamon is a potent immune system booster and consumption of cinnamon with honey strengthens the immune system.…”

Effect of Cinnamomum zeylanicum Essential Oil on Antioxidative Status in Broiler Chickens

“…2003). In a study of the wound healing action of an ethanol extract of cinnamon, the significant increase in wound healing was attributed to the antioxidant activity (Kamath et al 2003). Cinnamon constituents possess antioxidant action and may prove beneficial against free radical damage to cell membranes (Dragland et al 2003).…”