PRMT1 in human neoplasm: cancer biology and potential therapeutic target
Shiquan Shen,
Honglong Zhou,
Zongyu Xiao
et al.
Abstract:Protein arginine methyltransferase 1 (PRMT1), the predominant type I protein arginine methyltransferase, plays a crucial role in normal biological functions by catalyzing the methylation of arginine side chains, specifically monomethylarginine (MMA) and asymmetric dimethylarginine (ADMA), within proteins. Recent investigations have unveiled an association between dysregulated PRMT1 expression and the initiation and progression of tumors, significantly impacting patient prognosis, attributed to PRMT1’s involvem… Show more
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