Prm170 - Utilizing Patient Collages in Qualitative Interviews to Facilitate Data Collection in Patients Diagnosed With Ulcerative Colitis

Abstract

OBJECTIVES: Cost-utility analyses need a measure to summarize the quality of life in a single index. A single score is often obtained by the EQ-5D questionnaire which is adaptable to each country with score tariffs. In clinical studies it is common to use questionnaires that measure the quality of life profile, such as the SF-36 psychometric questionnaire and then realized the mapping technique to obtain this utility score. Today no specific regression method has been recommended for a such mapping. The purpose of the study is to compare the different regression methods for the conversion of SF-36 into EQ-5D with a French database. METHODS: The EMOCAR study was a French cohort of patients with carotid endarterectomy where 904 adults completed both EQ-5D and SF-36 questionnaires. Ordinary least squares (OLS) and multinomial logit models were implemented to predict the overall score and the response to each of the 5 categories of EQ-5D with two types of specifications: item-based and summary score-based of SF-36. The performance of each model was determined by the estimated average score, the absolute and mean squared errors as well as the percentage of errors. RESULTS: The model including SF-36 items using OLS method has the most accurate predictions comparing to other models. This mapping performance was indicated by a significant prediction of EQ-5D score of 0.7327 and by MAE (0.116), MSE (0.026), R 2 (0.67) and the percentage of an absolute error > 0.1 (43.71%). The model including SF-36 dimensions scores predicted an EQ-5D score significantly different from the EQ-5D observed score. OLS models predicted better EQ-5D score of younger subgroups and multinomial model with SF-36 items older subgroups. CONCLUSIONS: Our models suggest that models using OLS method have good performance for mapping SF-36 onto EQ-5D. Low scores are underpredicted with both models which is already present in the existing literature.

A qualitative study exploring the health-related quality of life and symptomatic experiences of adults and adolescents with ulcerative colitis

“…Another creative task used in this study involved asking participants to think about an animal which might represent their UC, and to explain their choice of animal. The value of creative tasks (such as collages and the animal task) to qualitative research has been shown to be particularly useful when interviewing younger participants in order to prompt discussion and orientate the participant to think about key areas of concern relating to their disease ahead of the interview [28]. Given the potential benefits of such a task, it was agreed to extend both tasks to adults as well as adolescent participants.…”

Qualitative research to explore the symptoms and impacts experienced by children with ulcerative colitis

“…All children were asked to develop and bring to their interview a collage representing their UC, though this was a voluntary activity and not required. If a collage was brought, the interviewer asked the participant to explain what each image represented, which allowed this information to facilitate coding [28]. A second creative task involved asking all child participants to think of an animal best representing their UC and probing their choice.…”

“…This was included to identify which aspect/s of their UC the child may see as most salient and allow further exploration of it in the interview. The value of such creative tasks to qualitative research has been shown to be particularly marked when interviewing younger participants in order to prompt discussion and orient the participant to think about key areas of concern relating to their disease ahead of the interview [28].…”