Prise en charge en FIV en cas d’endométriose, RPC Endométriose CNGOF-HAS

Chauffour, Candice; Pouly, Jean Luc; Grémeau, Anne-Sophie

doi:10.1016/j.gofs.2018.02.015

Cited by 3 publications

(1 citation statement)

References 57 publications

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“…In infertile women with endometriosis, neither the presence of endometriosis nor its stage appears to compromise IVF pregnancy and birth rates (LoE3) [25].…”

Section: Principles Of Ivf To Manage Infertility In Women With Endomementioning

confidence: 99%

Management of endometriosis

Collinet

Fritel

Revel-Delhom

et al. 2018

Journal of Gynecology Obstetrics and Human Reproduction

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First-line diagnostic investigations for endometriosis are physical examination and pelvic ultrasound. The second-line investigations are: targeted pelvic examination performed by an expert clinician, transvaginal ultrasound performed by an expert physician sonographer (radiologist or gynaecologist), and pelvic MRI. Management of endometriosis is recommended when the disease has a functional impact. Recommended first-line hormonal therapies for the management of endometriosis-related pain are combined hormonal contraceptives (CHCs) or the 52mg levonorgestrel-releasing intrauterine system (IUS). There is no evidence base on which to recommend systematic preoperative hormonal therapy solely to prevent surgical complications or facilitate surgery. After surgery for endometriosis, a CHC or 52mg levonorgestrel-releasing IUS is recommended as first-line treatment when pregnancy is not desired. In the event of failure of the initial treatment, recurrence, or multiorgan involvement, a multidisciplinary team meeting is recommended, involving physicians, surgeons and other professionals. A laparoscopic approach is recommended for surgical treatment of endometriosis. HRT can be offered to postmenopausal women who have undergone surgical treatment for endometriosis. Antigonadotrophic hormonal therapy is not recommended for patients with endometriosis and infertility to increase the chances of spontaneous pregnancy, including postoperatively. Fertility preservation options must be discussed with patients undergoing surgery for ovarian endometriomas.

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“…In infertile women with endometriosis, neither the presence of endometriosis nor its stage appears to compromise IVF pregnancy and birth rates (LoE3) [25].…”

Section: Principles Of Ivf To Manage Infertility In Women With Endomementioning

confidence: 99%

Management of endometriosis

Collinet

Fritel

Revel-Delhom

et al. 2018

Journal of Gynecology Obstetrics and Human Reproduction

Self Cite

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Prise en charge de l’endométriose : recommandations pour la pratique clinique CNGOF-HAS (texte court)

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Fritel

Revel-Delhom

et al. 2018

Gynécologie Obstétrique Fertilité & Sénologie

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Endometrial injury for patients with endometriosis and polycystic ovary syndrome undergoing medically assisted reproduction: current data and a protocol

Siristatidis

Rigos

Pergialiotis

et al. 2018

Hormone Molecular Biology and Clinical Investigation

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We propose a study protocol capable of improving clinical outcomes following medically assisted reproduction (MAR) in infertile women with endometriosis and polycystic ovary syndrome (PCOS). The proposed research derives from the published evidence on the positive impact from endometrial injury (EI) and the beneficial nature of the intervention towards improved implantation rates. We primarily refer to the cluster of events and hypotheses, such as the mechanical cascade, the inflammatory response per se, the events accompanying wound healing, the immune cell recruitment and protein involvement, alterations in gene expression and the neo-angiogenesis theories, which have been previously investigated for this purpose. We are also exploring the possible problems in MAR cycles with negative outcomes in PCOS and endometriosis patients and we are proposing potential mechanisms on how this intervention might work. Our hypothesis states that the EI before the initiation of the MAR cycle can affect clinical pregnancy rates in patients with the aforementioned pathologies.

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Prise en charge en FIV en cas d’endométriose, RPC Endométriose CNGOF-HAS

Cited by 3 publications

References 57 publications

Management of endometriosis

Management of endometriosis

Prise en charge de l’endométriose : recommandations pour la pratique clinique CNGOF-HAS (texte court)

Endometrial injury for patients with endometriosis and polycystic ovary syndrome undergoing medically assisted reproduction: current data and a protocol

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