Prise en charge diagnostique et thérapeutique des tumeurs épithéliales malignes de l’ovaire dans le centre ouest-africain de lutte contre le cancer de Dakar

Dem, Ahmadou; Dieng, Mamadou Moustapha; Ka, Sidy; Gaye, Papa Macoumba; Diouf, Doudou; Gaye-Fall, M C

doi:10.1684/bdc.2013.1693

Cited by 3 publications

(11 citation statements)

References 26 publications

(19 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The cumulative estimated crude overall 1-year and 2-year survival rate of our clinical patients (all histologic types) was 82.7% and 66.3%, respectively. The estimated 5-year survival rate was 33.9% (95% CI, 30.2%-37.6%), which is comparable to published data from Sudan (38%) but higher compared with data from Senegal (13%) [29,33]. Compared with population-based data from the U.S. with a 1-year and 2-year survival rate of 78.3% and 66.8%, respectively, in 2012, our population-based registry patients had worse outcome (of 73.9% and 51.8%) but not as huge of a difference as possibly expected given the limited therapy available [26].…”

Section: Survivalsupporting

confidence: 67%

“…In high-income countries the average age at diagnosis is comparatively higher, (e.g., in the U.S., 63 years; in Germany, 69 years) [2,26]. Reports from other sub-Saharan countries also show lower median ages, such as 45 years in Ghana, 52 years in Nigeria, and 49 years in Senegal [27][28][29]. The low median age in our patient cohort is attributable to the population structure in Ethiopia, where more than half of the population is younger than 20 years.…”

Section: Patient Characteristics: Age Distributionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical Characteristics and Survival of Patients with Malignant Ovarian Tumors in Addis Ababa, Ethiopia

et al. 2019

View full text Add to dashboard Cite

Background Ovarian cancer is the third leading cause of cancer death among women in Ethiopia, with about 2,550 diagnosed cases and 2,000 deaths each year. The incidence and mortality rates of this disease have been increasing in Ethiopia and other parts of sub‐Saharan Africa over the past decades because of changing lifestyle and reproductive factors. In this study, we describe the clinical characteristics, treatment patterns, and survival of patients with ovarian cancer in Ethiopia. Materials and Methods This retrospective cohort study included 485 patients diagnosed between January 2009 and October 2015 at Addis Ababa University Hospital, Zewditu Memorial Hospital, or registered in the Addis Ababa population‐based cancer registry. Follow‐up data were obtained via telephone. Primary endpoint was all‐cause mortality. Results The median age was 46 years (range, 11–95). The estimated 1‐ and 2‐year overall survival rates were 78% (95% confidence interval [CI] 0.741–0.82.5) and 59% (95% CI, 0.538–0.646), respectively. Of those patients with result available (n = 423), 73.0% had epithelial cancers. Almost half were classified as Federation of Gynecology and Oncology stage III or IV (48.2%; stage available n = 201) resulting in worse outcomes (hazard ratio [HR], 2.91 [CI 0.67–12.64] and 3.03 [0.69–15.79], respectively). Four out of five patients received some form of surgery (82%), three out of five received platinum‐containing chemotherapy. Patients with residual tumor after surgery (n = 83) showed worse survival outcome (HR, 2.23; 95% CI 1.08–4.49). Conclusion Our study revealed substantial treatment gaps with respect to surgery and adequate chemotherapy. Higher stage, residual tumor and lack of chemotherapy impaired the outcome. Access to higher standards of ovarian cancer treatment is urgently needed in Ethiopia. Implications for Practice Ovarian cancer is often a fatal disease in high resource settings; now it is also becoming important in Ethiopia. This study included 485 women with malignant ovarian tumors treated in Addis Ababa who had a mean age of only 46 years because of the young population structure. Three quarters had the typical epithelial cancer, with half presenting with advanced stage III and IV. Improved oncologic surgery and sufficient chemotherapy could possibly improve their outcome. The relatively high proportion of women with nonepithelial cancer need adequate treatment options to have good prognosis.

show abstract

Section: Survivalsupporting

confidence: 67%

Section: Patient Characteristics: Age Distributionmentioning

confidence: 99%

Clinical Characteristics and Survival of Patients with Malignant Ovarian Tumors in Addis Ababa, Ethiopia

et al. 2019

View full text Add to dashboard Cite

show abstract

“…The average age found in this study is higher than that reported by Raherinantenaina et al [10] in Madagascar which was 43 years. On the other hand, it is lower than the average age of 48.5 years reported by Sandoz et al [5] in Cameroon, that of 48.3 years found by Benhessou et al [4] in Morocco and that found by Dem et al [9] in Senegal which was 49 years old. Global overall figures show peak incidence of ovarian cancer between ages 65 and 74 [5].…”

Section: Discussionmentioning

confidence: 59%

“…On the other hand, it is lower than that of Benhessou et al [4] who found 56.6% of menopausal patients during their study. Dem et al [9] in Senegal found that more than half of the patients were menopausal at the time of diagnosis. All parities were affected by ovarian cancer with a predominance of multiparous and large multiparous women with a proportion of 32.6% and 21.5% respectively.…”

Section: Discussionmentioning

confidence: 99%

Ovarian Cancer: Clinical, Therapeutic and Prognostic Aspects at the University Hospital Center of Conakry in Guinea

Diallo,

Diallo

et al. 2023

OJOG

View full text Add to dashboard Cite

Background: Ovarian cancer is the seventh most common cancer in women in the world and is the leading cause of death among gynecological cancers. Objective: The objective of this study was to describe the clinical, therapeutic and prognostic aspects of ovarian cancer in the both Gynecology-Obstetrics departments Donka and Ignace Deen of the Conakry University Hospital. Methods: This was a retrospective, descriptive study lasting 12 years from January 1, 2011 to December 31, 2022, covering the files of patients treated for ovarian cancer in the both Gynecology-Obstetrics departments Donka and Ignace Deen. The study focused on the epidemiological, clinical, histological and therapeutic aspects of the disease. Results: In total, 135 files of patients with ovarian cancer were collected out of the 3821 files of gynecological pathologies recorded in the two departments during the study period, either a frequency of 3.5%. Among gynecological and breast cancers, ovarian cancer represented 9.1%. The average age of the patients was 46.3± 17.8 years and the average parity was 4 ± 3. The revealing clinical signs were dominated by pelvic pain (92.6%) and increased abdominal volume (53.3%). The diagnosis of the disease was made mainly at stages III and IV (71.9%). The most common histological type was serous papillary adenocarcinoma (57.0%). Exclusive surgical treatment was performed in 8.1% of patients, surgery combined with chemotherapy in 63.0% of patients and exclusive chemotherapy in 11.1% of patients. After an average follow-up of 42 months, 29 patients out of the 96 operated on were alive (30.2%), 51 had died (53.1%) and 16 patients were lost to follow-up (16.7%). Conclusion: Ovarian cancer is the third most common

show abstract

“…Sometimes it is one that occupies the first place and sometimes it is the other. Dem (Dem A, Dieng MM, Ka S & Diouf D, 2013) [7] in Senegal noted that cervical cancer (47.7%) ranks 1st and breast cancer (42%) ranks 2nd. Tonato Bagnan (Tonato Bagnan JA, Denakpo JL et al, 2013) [26] in Benin had reported a rate of 44.3% of cases for breast cancer and 26.7% of cases for cervical cancer.…”

Section: Discussionmentioning

confidence: 99%

Cancer patients' Perceptions and their Carers' Opinions of their Disease in Lubumbashi

Katumbo Mukemo,

Kabamba Nzaji,

Luboya Numbi

et al. 2024

IJAMRS

View full text Add to dashboard Cite

Background: Cancer poses significant challenges beyond its physical manifestations, impacting the psychosocial dimensions of patients and their caregivers. Understanding these complexities is crucial for delivering effective care. This study aims to explore the perceptions of cancer patients and their caregivers in Lubumbashi, Democratic Republic of Congo (DRC). Methods: A descriptive cross-sectional study was conducted from November 2016 to July 2017, involving female cancer patients and their caregivers from major hospitals in Lubumbashi. Data were collected using standardized questionnaires and analyzed quantitatively. Results: The majority of cancer patients were aged ≥45 years (88.9%), married (63.0%), and illiterate (44.4%). Cervical cancer (48.1%) was most prevalent, with late-stage diagnoses predominating. Only 22.2% of patients were informed of their diagnosis by a doctor. Palliative care was common (63.0%), reflecting advanced disease presentation. Caregivers reported significant financial challenges (92.6%) and anxiety (96.3%), suggesting unmet support needs. Conclusion: This study underscores the urgent need for improved cancer awareness, early detection, and psychosocial support services in Lubumbashi. Addressing the cultural, educational, and economic barriers to cancer care is essential for enhancing patient outcomes and caregiver well-being in the DRC.

show abstract

Prise en charge diagnostique et thérapeutique des tumeurs épithéliales malignes de l’ovaire dans le centre ouest-africain de lutte contre le cancer de Dakar

Cited by 3 publications

References 26 publications

Clinical Characteristics and Survival of Patients with Malignant Ovarian Tumors in Addis Ababa, Ethiopia

Clinical Characteristics and Survival of Patients with Malignant Ovarian Tumors in Addis Ababa, Ethiopia

Ovarian Cancer: Clinical, Therapeutic and Prognostic Aspects at the University Hospital Center of Conakry in Guinea

Cancer patients' Perceptions and their Carers' Opinions of their Disease in Lubumbashi

Contact Info

Product

Resources

About