Prise en charge chirurgicale des métastases cérébrales des cancers bronchopulmonaires

Faguer, R.; Terminassian, A.; Hureaux, J.; Soulié, P; Jadaud, É.; Meneï, Philippe

doi:10.1016/s1877-1203(12)70304-x

Cited by 3 publications

(1 citation statement)

References 67 publications

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“…In fact, it is the origin of 40-50% of all BM [1]. The increase in survival and improvement in quality of life, due to progress in systemic and local treatment, increases its incidence [2]. Smoking is the main causal factor.…”

Section: Introductionmentioning

confidence: 99%

Prognostic Factors Influencing the Survival of Patients with Brain Metastases from Lung Cancer

Ouafki

2023

AJBSR

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Introduction:The occurrence of brain metastases (BM) in patients with primary lung cancer, present at diagnosis or appearing later, is a frequent situation and constitutes a clinical entity known to have a poor prognosis: in 30 to 50% of non-small-cell lung cancers(NSCLC) , mostly adenocarcinomas.They impact overall survival and quality of life. Management is specific depending on the histology, the number of BM, whether or not they are symptomatic, life expectancy and clinical stage (oligometastatic or multimetastatic). Materials and Methods:This is a monocentric, retrospective observational study,including patients with NSCLC in the medical oncology department , at the Hassan II university hospital in Fez.Between January 2009 and January 2019, we evaluated the prognostic factors influencing the survival of patients with BM from NSCLC.Among the 489 NSCLC cases collected, 80 patients met the inclusion criteria. Conclusion:At the end of this study, the age, the performance status (PS) less than 2, encephalic radiotherapy, absence of extracranial metastases and female sex were associated with better survival. However, this association was statistically insignificant.

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Section: Introductionmentioning

confidence: 99%