Priority organic pollutant assessment of sludges for agricultural purposes

Abad, Esteban; Martínez, K.; Planas, Carles; Palacios, Òscar; Caixach, Josep; Rivera, J.

doi:10.1016/j.chemosphere.2005.03.018

Cited by 126 publications

(60 citation statements)

References 21 publications

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“…NPEs are also the only priority organic pollutants that are routinely found at greater concentrations than recommended in sewage sludges. Greater than 90% of Europe's sludges have more NPEs than their recommended limit; no other chemical exceeds its limits in more than 8% of the sludges (Abad et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Gender-specific induction of cytochrome P450s in nonylphenol-treated FVB/NJ mice

Hernández

Chapman

Kretschmer

et al. 2006

Toxicology and Applied Pharmacology

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Nonylphenol (NP) is a breakdown product of nonylphenol ethoxylates, which are used in a variety of industrial, agricultural, household cleaning, and beauty products. NP is one of the most commonly found toxicants in the United States and Europe and is considered a toxicant of concern because of its long half-life. NP is an environmental estrogen that also activates the pregnane X-receptor (PXR) and in turn induces P450s. No study to date has examined the gender-specific effects of NP on hepatic P450 expression. We provided NP at 0, 50 or 75 mg/kg/day for 7 days to male and female FVB/NJ mice and compared their P450 expression profiles. Q-PCR was performed on hepatic cDNA using primers to several CYP isoforms regulated by PXR or its relative, the constitutive androstane receptor (CAR). In female mice, NP induced Cyp2b10 and Cyp2b13, and downregulated the female-specific P450s, Cyp3a41 and Cyp3a44. In contrast, male mice treated with NP showed increased expression of Cyp2a4, Cyp2b9, and Cyp2b10. Western blots confirmed induction of Cyp2b subfamily members in both males and females. Consistent with the Q-PCR data, Western blots showed dose-dependent downregulation of Cyp3a only in females and induction of Cyp2a only in males. The overall increase in female-predominant P450s in males (Cyp2a4, 2b9) and the decrease in female-predominant P450s in females (Cyp3a41, 3a44) suggest that NP is in part feminizing the P450 profile in males and masculinizing the P450 profile in females. Testosterone hydroxylation was also altered in a genderspecific manner, as testosterone 16α-hydroxylase activity was only induced in NP-treated males. In contrast, NP-treated females demonstrated a greater propensity for metabolizing zoxazolamine probably due to greater Cyp2b induction in females. In conclusion, NP causes gender-specific P450 induction and therefore exposure to NP may cause distinct pharmacological and toxicological effects in males compared to females.

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Section: Introductionmentioning

confidence: 99%

Gender-specific induction of cytochrome P450s in nonylphenol-treated FVB/NJ mice

Hernández

Chapman

Kretschmer

et al. 2006

Toxicology and Applied Pharmacology

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“…This will save the need to buy chemical fertilizers resulting in cost saving and preventing excessive nutrient leaching from the soil caused by the application of chemical fertilizers. However, phthalic acid esters also tend to concentrate in biosolids because they have a low solubility in wastewater (Abad et al 2005). Application of municipal biosolids to agricultural land could thus lead to phthalic acid ester accumulation in the soil and phthalic acid ester uptake in plants (Table 1).…”

Section: Municipal Biosolidsmentioning

confidence: 99%

Contamination and remediation of phthalic acid esters in agricultural soils in China: a review

He¹,

Gielen²,

Bolan³

et al. 2014

Agron. Sustain. Dev.

229

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Phthalic acid esters have been used as plasticizers in numerous products and classified as endocrine-disrupting compounds. As China is one of the largest consumers of phthalic acid esters, some human activities may lead to the accumulation of phthalic acid esters in soil and result in contamination. Therefore, it is necessary for us to understand the current contamination status and to identify appropriate remediation technologies. Here, we reviewed the potential sources, distribution, and contamination status of phthalic acid esters in soil. We then described the ecological effect and human risk of phthalic acid esters and finally provided technologies to remediate phthalic acid esters. We found that (1) the application of plastic agricultural films, municipal biosolids, agricultural chemicals, and wastewater irrigation have been identified as the main sources for phthalic acid ester contamination in agricultural soil; (2) the distribution of phthalic acid esters in soils is determined by factors such as anthropogenic behaviors, soil type, properties of phthalic acid esters, seasonal variation, etc.; (3) the concentrations of phthalic acid esters in soil in most regions of China are exceeding the recommended values of soil cleanup guidelines used by the US Environmental Protection Agency (US EPA), causing phthalic acid ester in soils to contaminate vegetables; (4) phthalic acid esters are toxic to soil microbes and enzymes; and (5) phthalic acid ester-contaminated soil can be remedied by degradation, phytoremediation, and adsorption.

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“…Organic compounds identified in it include [8][9][10][11]: dioxins and furans, polychlorinated biphenyls (PCBs), organochlorine pesticides, adsorbed and extracted chloro derivatives, polycyclic aromatic hydrocarbons (PAHs), phenols and their derivatives, phthalates, sex hormones and others. The group of hazardous inorganic compounds assayed in sewage sludge contain primarily various heavy metals at a wide range of concentrations (mg/kg dry basis for raw sewage) [12][13][14][15][16][17][18]: arsenic 3-230, cadmium 1-3410, chromium 10-990,000, copper 80-2300, nickel 2-179, lead 13-465, and zinc 101-49,000.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Organic and Inorganic Contaminants in Dried Sewage Sludge and By-Products of Dried Sewage Sludge Gasification

Werle

Dudziak

2014

Energies

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Organic and inorganic contaminants in sewage sludge may cause their presence also in the by-products formed during gasification processes. Thus, this paper presents multidirectional chemical instrumental activation analyses of dried sewage sludge as well as both solid (ash, char coal) and liquid (tar) by-products formed during sewage gasification in a fixed bed reactor which was carried out to assess the extent of that phenomenon. Significant differences were observed in the type of contaminants present in the solid and liquid by-products from the dried sewage sludge gasification. Except for heavy metals, the characteristics of the contaminants in the by-products, irrespective of their form (solid and liquid), were different from those initially determined in the sewage sludge. It has been found that gasification promotes the migration of certain valuable inorganic compounds from sewage sludge into solid by-products which might be recovered. On the other hand, the liquid by-products resulting from sewage sludge gasification require a separate process for their treatment or disposal due to their considerable loading with toxic and hazardous organic compounds (phenols and their derivatives).

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Priority organic pollutant assessment of sludges for agricultural purposes

Cited by 126 publications

References 21 publications

Gender-specific induction of cytochrome P450s in nonylphenol-treated FVB/NJ mice

Gender-specific induction of cytochrome P450s in nonylphenol-treated FVB/NJ mice

Contamination and remediation of phthalic acid esters in agricultural soils in China: a review

Analysis of Organic and Inorganic Contaminants in Dried Sewage Sludge and By-Products of Dried Sewage Sludge Gasification

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