Printed composite electrodes for in-situ wound pH monitoring

Sharp, Duncan

doi:10.1016/j.bios.2013.06.042

Cited by 49 publications

(28 citation statements)

References 39 publications

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“…36,57 However, the wound is a complex, nonhomogenous environment and most of these products can only provide the value of pH at any given point instead of the entire wound landscape. [35][36][37] Also, previous studies have shown that when healing begins, wound environment typically changes from alkaline to neutral and then to an acidic state. 11,18,26,58 While wound alkalinity is an important prognostic factor of nonhealing wounds, no major attempt has been made to link this to wound healing activities.…”

Section: Discussionmentioning

confidence: 99%

“…Also, they provide an average pH only at the single point of contact instead of the entire wound. [35][36][37] pH strips have been widely used in detecting infections in the wound as well as in the urinary tract, vagina, and in the evaluation of salivary pH in human immunodeficiency viruspositive individuals. However, like the pH meter, pH strips cannot be used to assess the entire wound landscape.…”

Section: Introductionmentioning

confidence: 99%

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A Device to Predict Short-Term Healing Outcome of Chronic Wounds

Tran

Pal

et al. 2020

Advances in Wound Care

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Objective: While myriads of studies have suggested that a survey of wound pH environment could indicate wound healing activities, it is not clear whether wound alkalinity can be used as a prognostic indicator of nonhealing wounds. Currently available systems cannot reliably assess the pH environment across wounds, which is the objective of this study. Approach: A disposable device, DETEC Ò pH, was developed and characterized on its ability to map wound alkalinity by pressing a freshly recovered wound dressing against its test surface. By comparing the wound's alkalinity and size reduction rates (*7 days) following pH measurement, we assessed the capability of wound alkalinity to prognosticate subsequent short-term wound size reduction rates. Results: The device had high accuracy and specificity in determining the alkalinity of simulated wound fluids soaked onto wound dressing. The type of wound dressing type had an insignificant effect on its detection sensitivity. Upon testing discarded wound dressings from human patients, the device quickly determined alkaline and acidic wounds. Finally, statistical analyses of wound size reduction rates in wounds with various alkalinities confirmed that wound alkalinity has a strong influence on, at least, short-term wound healing activity. Innovation: Without directly contacting the patient, this device provides a quick assessment of wound alkalinity to prognosticate immediate and short-term wound healing activities. Conclusion: DETEC Ò pH may serve as a prognosis device for wound care specialists during routine wound assessment to predict wound healing progress. This information can assist the decision-making process in a clinical setting and augur well for chronic wound treatment. DETEC Ò pH can also be used as an aid for home health care nurses or health care providers to screen nonhealing wounds outside clinics.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Device to Predict Short-Term Healing Outcome of Chronic Wounds

Tran

Pal

et al. 2020

Advances in Wound Care

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“…However, the conventional glass pH probe only provides localized measurements and does not provide complex measurements for the whole wound area. 10,11 Wound pH is currently not a factor that is routinely measured clinically. Increasing evidence suggests that chronic wounds are in a state of alkalinity such that, if further studies proved that pH does play an important role in nonhealing wounds, simple pH measurements in a hospital setting could make it possible to identify and diagnose nonhealing wounds earlier.…”

Section: Discussionmentioning

confidence: 99%

The Effect of pH on the Extracellular Matrix and Biofilms

Jones

Cochrane

Percival

2015

Advances in Wound Care

332

252

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“…Images of the wound surface might result in pseudocolor pH maps of the area [66]. A new technology might be also printed composite electrodes for in situ wound pH monitoring [67]. …”

Section: Wound Diagnosticsmentioning

confidence: 99%

Recent Developments in Topical Wound Therapy: Impact of Antimicrobiological Changes and Rebalancing the Wound Milieu

Erfurt‐Berge

Renner

2014

BioMed Research International

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Wound therapy improves every year by developing new wound treatment options or by advancing already existing wound materials, for example, adding self-releasing analgesic drugs or growth factors to wound dressings, or by binding and inactivating excessive proteases. Also new dressing materials based on silk fibers and enhanced methods to reduce bacterial burden, for example, cold argon plasma, might help to fasten wound healing.

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Printed composite electrodes for in-situ wound pH monitoring

Cited by 49 publications

References 39 publications

A Device to Predict Short-Term Healing Outcome of Chronic Wounds

A Device to Predict Short-Term Healing Outcome of Chronic Wounds

The Effect of pH on the Extracellular Matrix and Biofilms

Recent Developments in Topical Wound Therapy: Impact of Antimicrobiological Changes and Rebalancing the Wound Milieu

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