Prins Reaction

Abstract

This reaction is an acid‐catalyzed condensation between aldehydes and olefins to form a variety of compounds such as 1,3‐dioxanes, 1,3‐diols, allyl alcohols, or 1,3‐diesters, depending on the nature of alkenes and the reaction conditions and is generally referred to as the Prins reaction. All the reactants for this reaction including Lewis acid and Brønsted acid have been summarized. It has been reported that the reaction produces good results when sulphuric acid is used as catalyst On the other hand, this reaction has been found to be highly stereoselective with trans ‐addition for both alicyclic and acylic olefins. This reaction is very useful and has been applied for the production of dienes in large quantities for synthetic rubber manufacturing.