Principles of Surgical Care—Shock and Other Problems

Studies on Myocardial Metabolism. III. Coronary Blood Flow, Myocardial Oxygen Consumption and Carbohydrate Metabolism in Experimental Hemorrhagic Shock12

“…A series of reports have been published on the cause of irreversibility from hemorrhagic shock (1)(2)(3)(4)(5). Wiggers and Werle (2,3), on the basis of pressure and volume curves obtained from dogs during various phases of hemorrhagic shock, suggested the possibility that the deterioration of myocardial expulsive power contributed to circulatory failure and that this myocardial depression contributed to the reappearance of circulatory failure during the normovolemic phase.…”

Acute Coronary Insufficiency Due to Acute Hemorrhage: An Analysis of One Hundred and Three Cases

“…Abnormal T waves alone aswere observed in 24 cases, ItS-T depression alone in 4 and combined RS-T and T changes in 25 cases. The mortality rate of the 24 cases showing Twave changes alone was only 17 per cent as compared with a rate of 40 per cent in the 25 patients who had presented 1{S-T depression in association with T-wave changes. It seems, therefore, that a combination of RS-T segment depression and T-wave inversion represents a more profound degree of coronary insufficiency than a change in the T wave alone.…”

The Relationship of Dehydration and Overhydration of the Blood Plasma to Collapse in the Management of Artificial Fever Therapy 1

“…This illustrates an observation noted many times in the same individual receiving fever therapy in two different seasons of the year. Bazett et al (34) has reported differences in blood volume in summer and winter. Barcroft et al (4), by means of the carbon monoxide method of blood volume measurement, showed an average increase of 10 to 25 per cent in blood volume in subjects who travelled from England through the tropics.…”

“…A single prolonged fever is still often given for the treatment of refractory cases of gonorrhea (32,34), and is also being used in our clinic for the treatment of paresis, whenever feasible. Four selected cases of rheumatoid arthritis were given experimental 48-hour treatments at a temperature of 39.5°C.…”