Principles of motion control of bacterial micro-robots using oxygen gradients

Shechter, Evan

doi:10.1109/aim.2010.5695944

Cited by 5 publications

(4 citation statements)

References 13 publications

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“…Oxygen can be a strong attractant for some microorganisms. Shechter et al [ 37 ] demonstrated that bacteria actively moved via oxygen gradient in the medium from the lowest concentration to the highest. It is necessary to mention that magnetotactic bacteria were used in this study, which provides an opportunity to investigate joint control by using magnetic field and oxygen concentration gradients.…”

Section: Current Approaches In the Microbial Cell Based Microrobots D...mentioning

confidence: 99%

Microbial Cells as a Microrobots: From Drug Delivery to Advanced Biosensors

Готовцев

2023

Biomimetics

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The presented review focused on the microbial cell based system. This approach is based on the application of microorganisms as the main part of a robot that is responsible for the motility, cargo shipping, and in some cases, the production of useful chemicals. Living cells in such microrobots have both advantages and disadvantages. Regarding the advantages, it is necessary to mention the motility of cells, which can be natural chemotaxis or phototaxis, depending on the organism. There are approaches to make cells magnetotactic by adding nanoparticles to their surface. Today, the results of the development of such microrobots have been widely discussed. It has been shown that there is a possibility of combining different types of taxis to enhance the control level of the microrobots based on the microorganisms’ cells and the efficiency of the solving task. Another advantage is the possibility of applying the whole potential of synthetic biology to make the behavior of the cells more controllable and complex. Biosynthesis of the cargo, advanced sensing, on/off switches, and other promising approaches are discussed within the context of the application for the microrobots. Thus, a synthetic biology application offers significant perspectives on microbial cell based microrobot development. Disadvantages that follow from the nature of microbial cells such as the number of external factors influence the cells, potential immune reaction, etc. They provide several limitations in the application, but do not decrease the bright perspectives of microrobots based on the cells of the microorganisms.

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Section: Current Approaches In the Microbial Cell Based Microrobots D...mentioning

confidence: 99%

Microbial Cells as a Microrobots: From Drug Delivery to Advanced Biosensors

Готовцев

2023

Biomimetics

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“…Many bio-inspired swimming robots rely on tethered power supplies or onboard batteries, which are not suitable for microrobots [6,7]. A number of actuation methods for micron-sized devices can be found in literature, including the use of real bacteria to move micro-objects [8][9][10] or the use of chemically fuelled devices [11][12][13]. Both of these methods provide onboard actuation but are limited in the types of environments that can be employed.…”

Section: Introductionmentioning

confidence: 99%

Magnetic polymer composite artificial bacterial flagella

et al. 2014

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Artificial bacterial flagella (ABFs) are magnetically actuated swimming microrobots inspired by Escherichia coli bacteria, which use a helical tail for propulsion. The ABFs presented are fabricated from a magnetic polymer composite (MPC) containing iron-oxide nanoparticles embedded in an SU-8 polymer that is shaped into a helix by direct laser writing. The paper discusses the swim performance of MPC ABFs fabricated with varying helicity angles. The locomotion model presented contains the fluidic drag of the microrobot, which is calculated based on the resistive force theory. The robot's magnetization is approximated by an analytical model for a soft-magnetic ellipsoid. The helicity angle influences the fluidic and magnetic properties of the robot, and it is shown that weakly magnetized robots prefer a small helicity angle to achieve corkscrew-type motion.

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“…Controlled swimming of bio-inspired robots is crucial to high precision in-vivo and in-vitro applications [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Experimental validation of a CFD-based resistive force coefficient set for rotating helical tails in cylindrical channels

Tabak¹,

Yeşilyurt²

2013

WIT Transactions on the Built Environment

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Real-time manipulation of objects in micro flows is important due to an ever increasing interest in demanding medical applications. Specialized swimming micro robots are expected to perform minimal invasive surgery consisting of various in vivo tasks. Moreover, fluid forces exerted on moving surfaces are crucial for maneuverability if swimming micro robotic tools are ever to play a key role in therapeutic applications. Hydrodynamic forces acting on an isolated object of regular blunt shapes immersed in micro flows are calculated by resistive force coefficients based on the Stokes Flow approximation derived by analytical means. However, force coefficients presented in literature often lack the accuracy to predict the hydrodynamic interactions between rotating and translating objects of irregular shapes, and rigid concave surfaces such as a rigid helix moving inside a cylindrical channel. In this study a set of parameterized 3D CFD simulations are carried out using a novel geometric representation for rigid helical tails of varying sizes and of varying distances with respect to the wall of a cylindrical channel. Furthermore, the complex rigid-body motion of the helix is represented by a series of simple translations and rotations. Each simulation is governed by Stokes equations and carried out by a commercial CFD package. A generic resistive force coefficient set is obtained via surface-fit procedures based on the hydrodynamic forces computed by the CFD simulations along the tangential, normal and binormal directions on the moving and rotating helical surface. Finally, using a reduced-order microhydrodynamic model, the proposed coefficient set is validated with empirical data collated using bio-inspired cm- scale robots autonomously swimming in a cylindrical channel filled with silicone oil of high viscosity. The robots are on-board powered and propel themselves with rotating rigid helices of parameterized geometric features. The CFD-based coefficient set predicted the experiment-based velocities of the bio-inspired untethered robots with good agreement.

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Principles of motion control of bacterial micro-robots using oxygen gradients

Cited by 5 publications

References 13 publications

Microbial Cells as a Microrobots: From Drug Delivery to Advanced Biosensors

Microbial Cells as a Microrobots: From Drug Delivery to Advanced Biosensors

Magnetic polymer composite artificial bacterial flagella

Experimental validation of a CFD-based resistive force coefficient set for rotating helical tails in cylindrical channels

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