Principles of Gene Therapy in Reconstructive and Regenerative Surgery

Giatsidis, Giorgio

doi:10.1007/978-3-319-78957-6_1

Cited by 1 publication

(1 citation statement)

References 57 publications

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“…This high rate of hypertrophic scar following primary cleft lip repair is usually associated with high dissatisfaction among surgeons and patients and multiple revision procedures throughout childhood in order to correct this problem. 6,7 In this study, botulinum toxin was used in primary cheiloplasty and its effects were evaluated for reducing or preventing hypertrophic scar following primary cleft lip repair.…”

Section: Introductionmentioning

confidence: 99%

Evaluating the effects of botulinum toxins to minimize post cleft lip hypertrophic scar

A Jassim

2023

IqNJM

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Abstract: Background: Cleft lip deformity is one of the most common congenital anomalies. Repair of cleft lip may create too much tension especially when done in wide cleft lip, and this may result in unacceptable scar. Aim of study: To evaluate the efficacy of botulinum toxin in reducing or preventing post cheiloplasty hypertrophic scar. Patient and method: Between the period from October 2019 to August 2021, 10 patients with cleft lip were subjected to primary cheiloplasty using Millard rotation advancement flap technique followed by botulinum toxin injection into the site of repair. Follow up period was 6 months postoperatively. Results: All of our patients showed excellent result which was evaluated using visual analogue scale assessment which was done by tow independent surgeons. Our patients showed barely visible scar at 6 months postoperatively with no recorded hypertrophic scar. No side effect was recorded related to botulinum toxin injection. Conclusion: Botulinum toxin injection after primary cheiloplsty showed to be safe and effective in prevention of development of unacceptable hypertrophic scar. Keywards: botulinum, cleft lip, hypertrophic scar, cheiloplasty.

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Section: Introductionmentioning

confidence: 99%

Evaluating the effects of botulinum toxins to minimize post cleft lip hypertrophic scar

A Jassim

2023

IqNJM

View full text Add to dashboard Cite

show abstract

Principles of Gene Therapy in Reconstructive and Regenerative Surgery

Cited by 1 publication

References 57 publications

Evaluating the effects of botulinum toxins to minimize post cleft lip hypertrophic scar

Evaluating the effects of botulinum toxins to minimize post cleft lip hypertrophic scar

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