Principles for the surgical management of patients with Proteus syndrome and patients with overgrowth not meeting Proteus criteria

Connective tissue nevi in children: Institutional experience and review

“…CTN almost always have a polylobulated surface, but when they are deep-seated, especially on the plantar surface of the feet, they can develop a cerebriform aspect. [3][4][5][6][7][8][9][10][11][12][13] Classification of CTN was established by Uitto et al 1 in 1980 according to clinical, histopathologic, and genetic features. 1 Our review suggested a modified classification, able to categorize almost all our cases (Table II).…”

“…34 PS presents with a distinctive clinicopathologic form of CTN as seen in 3 of our patients. 3,[11][12][13][14] An indepth discussion of this syndrome is beyond the scope of this article. 11 Our patient with a cerebriform plantar collagenoma treated by skin grafting and carbon-dioxide laser had an excellent result even after 7 years, with minimal recurrence at the edge.…”

Proteus syndrome: what the anesthetist should know

“…Hamartomas and lipomas of the gut can lead to intussusceptions, acute intestinal obstruction, gastric outlet obstruction, and rectal prolapse [6]. There is also a risk of increased bleeding during gastrointestinal surgeries due to intestinal vascular malformations.…”

“…Patients may also require genitourinary, gastrointestinal, otolaryngological, or tumor excision surgeries for treatment of complications of PS [6]. Because of the complexity of the disorder, the anesthetic problems encountered during patients' perioperative management are very varied.…”

Craniofacial hyperostoses in Proteus syndrome – a case report

“…(Biesecker, 2001). Lesions of the genital glands may require more aggressive treatment due to the high incidence of neoplasia (Lublin et al, 2002). In the craniofacial area, reduction procedures of soft and hard tissues are mainly indicated due to the typical overgrowth.…”