Principles and Syndromes of Enteric Infection

Prolonged Episodes of Acute Diarrhea Reduce Growth and Increase Risk of Persistent Diarrhea in Children

“…In general, infectious disease and pediatric GI texts use the WHO cutoff of ≥2 weeks to delineate persistent from acute episodes 34,35. Some experts use “chronic” for illnesses lasting >30 days 36.…”

Looking for Cryptosporidium: the application of advances in detection and diagnosis

“…Increased morbidity, mortality, and socioeconomic implications [6,7] are recognised by inclusion of Cryptosporidium in the Neglected Diseases Initiative of the World Health Organization (WHO) [8]. Cryptosporidiosis is a laboratory diagnosis because it is not pathognomonic -in other words, the acute signs and symptoms can be similar to other infectious and non-infectious causes of gastroenteritis [9,10]. In cases where other parasites are also suspected, or in populations where they are prevalent, multiple faecal samples with and without chemical preservation may be required [11] (Figure 2).…”

Comparison of the BD MAX Enteric Bacterial Panel to Routine Culture Methods for Detection of Campylobacter, Enterohemorrhagic Escherichia coli (O157), Salmonella, and Shigella Isolates in Preserved Stool Specimens

“…The diagnosis of bacterial pathogens is particularly challenging given the large amount of vastly diverse indigenous gastrointestinal flora present in stool (1). There are approximately 10 11 bacteria per gram of stool, a population consisting of anaerobes, Escherichia coli, Klebsiella, Proteus, enterococci, and others (2). Individual bacterial populations in stool are very fluctuant, showing changes in response to a variety of environmental cues ranging from antibiotic use to inflammation.…”