Principles and practical methods of curing tobacco

Garner, W. W.

doi:10.5962/bhl.title.35135

Cited by 14 publications

(24 citation statements)

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“…When the various approximations were corrected for redundancy, it was found that the amount of information reproduced at each exposure was the same for all four approximations. This result has been interpreted by Miller et aE., and by subsequent writers (Cherry, 1957, p. 280-4; Garner, 1962, p. 252-5; Vernon, 1962, p. 109-10) as a perceptual effect.…”

Section: Introductionsupporting

confidence: 50%

Immediate Memory and the “Perception” of Letter Sequences

Baddeley

1964

Quarterly Journal of Experimental Psychology

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It is suggested that the relationship observed by Miller, Bruner and Postman (1954) between the redundancy and the accuracy of reproduction of tachistoscopically presented letter sequences is not a perceptual effect as they suggest, but is due to the informational limitations of immediate memory. An experiment is performed which shows an exactly similar relationship between redundancy and number of letters correctly reproduced when exposure time is long enough for the subject to read out, and hence perceive, all the material with complete accuracy. It is concluded that the more redundant the letter sequence and the longer the exposure time, the more effectively the sequence can be coded and the better it will be recalled.

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Section: Introductionsupporting

confidence: 50%

Immediate Memory and the “Perception” of Letter Sequences

Baddeley

1964

Quarterly Journal of Experimental Psychology

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“…The compounds can be used for treating presbyopia, cataract, macular degeneration e.g. age-related macular degeneration, retinopathies such as diabetic retinopathy, glaucoma, and ocular inflammations [218]. Dithiol compounds and derivatives thereof are disclosed.…”

Section: Ocular Targeting Of Therapeutic Imi-dazole-containing Dipeptmentioning

confidence: 99%

Structural and Functional Properties, Chaperone Activity and Posttranslational Modifications of Alpha-Crystallin and its Related Subunits in the Crystalline Lens: N-acetylcarnosine, Carnosine and Carcinine act as Alpha- Crystallin/Small Heat Shock Protein Enhancers in Prevention and Dissolution of Cataract in Ocular Drug Delivery Formulations of Novel Therapeutic Agents

Babizhayev¹

2012

DDF

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Cataract is a leading cause of blindness worldwide and is responsible for ∼40-80% of the estimated 45 million cases of blindness that occur across the globe. In addition to providing refractive properties to the lens for focusing the image, it is believed that the molecular chaperone function of α-crystallin is essential in preventing the light scattering due to aggregation of other proteins and thus in the maintenance of lens transparency and thereby prevention of cataract. By now, it is fairly acknowledged that chaperoning ability of α-crystallin is instrumental in the maintenance of crystalline lens transparency, and decreased chaperone-like activity of α-crystallin is associated with various types and stages of cataract. A better pharmacological targeting of safeguarding the α-crystallin chaperone activity may aid the development of therapeutic strategies that could evade the need for cataract surgery and revive lens transparency of the cataractous lenses. This article originally summarizes the significance of modulation and enhancing of α-crystallin chaperone activity with imidazole-containing dipeptides N-acetylcarnosine, carnosine and carcinine in consequence to prevent, delay or dissolve the human cataract. A growing evidence and discussion of recent patents are presented in this study that demonstrate the ability of N-acetylcarnosine (lubricant eye drops) or carcinine (lubricant eye drops) (universal antioxidant and deglycation agent) resistant to enzymatic hydrolysis with carnosinase to act as pharmacological chaperones, to decrease oxidative stress and ameliorate oxidative and excessive glycation stress-related eye disease phenotypes, suggesting that the field of chaperone therapy might hold novel treatments for age-related cataracts, age-related macular degeneration (AMD) and ocular complications of diabetes (OCD). The therapeutic strategies are highlighted in the study for identifying potential chaperone compounds and for experimentally demonstrating chaperone activity in in vitro and in vivo models of human age-related eye disease, such as cataracts and advanced glycation tissue proteins - engineered systems.

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“…In the model, it was assumed that in the aggregation chimeras of mice, the blastomeres of allogeneic origin do not mingle freely during the course of early differentiation of germ layers; this assumption was based upon the experimental findings reported independently by several investigators (6,13,26). Then, the primary ectoderm of the chimeric blastocyst may be envisaged as a sheet of circular germ layer where the two cell populations are distributed not in the salt-andpepper patterns (Fig.…”

Section: Analysis With Modelsmentioning

confidence: 99%

Possible Patterns of Differentiation in the Primitive Ectoderm of C3H/HeNBALB/cA Chimeric Blastocysts: An Inference from Quantitative Analysis of Coat‐Color Patterns

1991

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Coat-color patterns of 20 C3H/HeNoBALB/cA chimeras produced by using the same colony of mice in a series of experiments, were quantitatively analyzed, by means of a video-image analysis system developed by Tachi (1988Tachi ( , 1989. In those chimeras, proportion of the two allogeneic components, i.e., C3H/HeN and BALB/cA, was relatively well balanced between the right and the left halves of the pelts, whereas between the anterior and the posterior regions it was unbalanced in favor of BALBIcA components in the anterior region. To interpret the results, a computerized geometrical model intended to simulate the hypothetical conditions of chimeric germ layers during early embryogenesis, was constructed. From the model, it was proposed that the seemingly high selection pressure for the BALB/cA components in the anterior region of this particular group of chimeras, might have been caused because the initial steps of the determination of the cranio-caudal axis took place in the regions of the primary ectoderm where BALBIcA, rather than C3HIHeN blastomeres were predominant. Possible variations in the alleles of the genes regulating the germ layer differentiation, might conceivably be the cause for the observed tendencies.

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Principles and practical methods of curing tobacco

Cited by 14 publications

References 0 publications

Immediate Memory and the “Perception” of Letter Sequences

Immediate Memory and the “Perception” of Letter Sequences

Possible Patterns of Differentiation in the Primitive Ectoderm of C3H/HeNBALB/cA Chimeric Blastocysts: An Inference from Quantitative Analysis of Coat‐Color Patterns

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