Primum Non Nocere

Rostenberghe, Hans Van

doi:10.21315/mjms2021.28.1.17

Cited by 3 publications

(2 citation statements)

References 3 publications

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“…In a recent report [47], the link between vaccinations and the principles of biomedical ethics has been discussed by assessing four fundamental principles: autonomy (freedom of choice: mandatory and non-mandatory), non-maleficence (not causing harm), beneficence (promoting good), and legality. Several international authors have focused on this topic individually [48,49], suggesting that an international vaccination program should follow seven ethical principles [49]:…”

Section: Discussionmentioning

confidence: 99%

Autopsy Findings and Causality Relationship between Death and COVID-19 Vaccination: A Systematic Review

Sessa

Salerno

Esposito

et al. 2021

JCM

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The current challenge worldwide is the administration of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine. Considering that the COVID-19 vaccination represents the best possibility to resolve this pandemic, this systematic review aims to clarify the major aspects of fatal adverse effects related to COVID-19 vaccines, with the goal of advancing our knowledge, supporting decisions, or suggesting changes in policies at local, regional, and global levels. Moreover, this review aims to provide key recommendations to improve awareness of vaccine safety. All studies published up to 2 December 2021 were searched using the following keywords: “COVID-19 Vaccine”, “SARS-CoV-2 Vaccine”, “COVID-19 Vaccination”, “SARS-CoV-2 Vaccination”, and “Autopsy” or “Post-mortem”. We included 17 papers published with fatal cases with post-mortem investigations. A total of 38 cases were analyzed: 22 cases were related to ChAdOx1 nCoV-19 administration, 10 cases to BNT162b2, 4 cases to mRNA-1273, and 2 cases to Ad26.COV2.S. Based on these data, autopsy is very useful to define the main characteristics of the so-called vaccine-induced immune thrombotic thrombocytopenia (VITT) after ChAdOx1 nCoV-19 vaccination: recurrent findings were intracranial hemorrhage and diffused microthrombi located in multiple areas. Moreover, it is fundamental to provide evidence about myocarditis related to the BNT162B2 vaccine. Finally, based on the discussed data, we suggest several key recommendations to improve awareness of vaccine safety.

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Section: Discussionmentioning

confidence: 99%

Autopsy Findings and Causality Relationship between Death and COVID-19 Vaccination: A Systematic Review

Sessa

Salerno

Esposito

et al. 2021

JCM

View full text Add to dashboard Cite

show abstract

“…However, regardless of the emergency, some corners must never be cut, particularly those that, if overlooked, could seriously impact human health. In other words, even emergency public health measures should heed the fundamental premise of primum non nocere , perhaps one of the main precepts of bioethics that all medical students are taught throughout the world [7] , [8] . Although it can be argued that every preventative or therapeutic pharmacological intervention is a two-edged sword if we consider every single potential side effect that could be associated with its use [9] , before consenting to receiving the COVID-19 mRNA vaccines, recipients must certainly be informed about what is known and what is not known in terms of immediate- and long-term safety.…”

Section: Introductionmentioning

confidence: 99%