Primitive neuroectodermal tumor of the kidney: A rare case report

Abstract

Renal primitive neuroectodermal tumor (PNET) is a rare primary renal neoplasm. Morphologically, it may mimic small blue round-cell tumor. Hence, histopathology in conjunction with immunohistochemistry plays a significant role in correctly diagnosing this malignancy. We report a case of PNET of kidney in a 30-year-old female with an extension to inferior vena cava, who succumbed following an aggressive course of illness.

Primitive neuroectodermal tumor (PNET)/Ewing sarcoma of kidney: A rare case report of three cases

“…Renal PNET/ESis a member of Ewing sarcoma family. [1][2][3] They are rare tumors originating from the neural crest and are more aggressive than PNET at any other site. 5 Rafael et al in study of 11 cases observed that most common age of diagnosis was between 18 to 45 years.…”

“…2 They are commonly confused with other small round cell tumors.Also clinical findings are very similar to other renal malignancies, hence histopathology and immunohistochemistry remains the gold standard for confirming the diagnosis. 3,4 We report three cases of PNET / Ewing sarcoma .Two patients were males 25 and 35 years and third patient was25 year old female. Histopathology showed malignant small round cells in sheets and diagnosis was confirmed on immunohistochemistry.…”