Primary umbilical endometriosis successfully treated with dienogest

Chew, Kah Teik; Norsaadah, Salim; Suraya, A G Ani; Hing, Erica Yee; Zainuddin, Ani Amelia; Azlin, Mohd Ismail Nor; Azurah, Abdul Ghani Nur

doi:10.1515/hmbci-2016-0017

Cited by 3 publications

(3 citation statements)

References 13 publications

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“…Medical management widely used hormonal therapy like oral contraceptive pills, dienogest and GnRH antagonist have been mentioned in literature and have been effective in relieving the symptoms but disease progression is not halted by medical therapy so recurrence of symptoms and growth of lesions is the major drawback [16] .…”

Section: Discussionmentioning

confidence: 99%

Primary Umbilical endometriosis - case series and review of clinical presentation, diagnosis and management

Bindra

Sampurna

Kade³

et al. 2022

International Journal of Surgery Case Reports

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Section: Discussionmentioning

confidence: 99%

Primary Umbilical endometriosis - case series and review of clinical presentation, diagnosis and management

Bindra

Sampurna

Kade³

et al. 2022

International Journal of Surgery Case Reports

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“…Twenty-nine published studies with primary umbilical endometriosis were identified in the literature written in English and Korean language during the period 2000~2016 ( Table 1 ) 1 3 4 5 6 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 . Primary umbilical endometriosis is initially very rare condition, but it is now increasing in number.…”

Section: Discussionmentioning

confidence: 99%

Primary Cutaneous Endometriosis of Umbilicus

2017

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Cutaneous endometriosis is defined by the presence of endometrial glands and/or stroma in skin and represents less than 1% of all ectopic endometrium. Cutaneous endometriosis is classified as primary and secondary. Primary cutaneous endometriosis appears without a prior surgical history and secondary cutaneous endometriosis mostly occurs at surgical scar tissue after abdominal operations. The most widely accepted pathogenesis of secondary endometriosis is the iatrogenic implantation of endometrial cells after surgery, such as laparoscopic procedures. However, the pathogenesis of primary endometriosis is still unknown. Umbilical endometriosis is composed only 0.4% to 4.0% of all endometriosis, however, umbilicus is the most common site of primary cutaneous endometriosis. A 38-year-old women presented with solitary 2.5×2.0-cm-sized purple to brown colored painful nodule on the umbilicus since 2 years ago. The patient had no history of surgical procedures. The skin lesion became swollen with spontaneous bleeding during menstruation. The skin lesion was diagnosed as a keloid at private hospital and has been treated with lesional injection of steroid for several times but there was no improvement. Imaging studies showed an enhancing umbilical mass without connection to internal organs. Biopsy specimen showed the several dilated glandular structures in dermis. They were surrounded by endometrial-type stroma and perivascular infiltration of lymphocytes. The patient was diagnosed as primary cutaneous endometriosis and skin lesion was removed by complete wide excision without recurrence. We report an interesting and rare case of primary umbilical endometriosis mistaken for a keloid and review the literatures.

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“…In a review of PUE literature published during the period 2015-2020, seventeen studies were identified written in English or French language (Table 1) [9,13,[22][23][24][26][27][28][29][30][31][32][33][34][35][36][37]. Based on all reports, the mean age of patients with PUE was 36.3 years.…”

Section: Discussionmentioning

confidence: 99%

“Umbilical mass”: a case of primary umbilical endometriosis and literature review

Pan¹,

Tang²,

Li³

et al. 2021

Clinical and Experimental Obstetrics & Gynecology

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Background: To report on a case of primary Umbilical Endometriosis (PUE). Case: We report a new rare case of PUE in a 45-year-old woman arising in the umbilicus, presenting as three purple-blue firm masses with a smooth surface, and clear borders. The patient presented to our hospital with a complaint of dark-red blood flowing out of the umbilical fossa accompanied by periodic menstrual pain for more than a year. PUE was initially diagnosed based on clinical signs and imaging studies and the mass was widely excised. The postoperative histologic examination of the tissue confirmed the diagnosis of PUE. Conclusion: PUE is a rare umbilical disorder. Its diagnosis may be complicated due to clinician lack of knowledge. The possibility of endometriosis must be considered during the evaluation of an umbilical mass despite the absence of any previous surgery, with special attention to menstrual symptoms or bloody discharge.

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Primary umbilical endometriosis successfully treated with dienogest

Cited by 3 publications

References 13 publications

Primary Umbilical endometriosis - case series and review of clinical presentation, diagnosis and management

Primary Umbilical endometriosis - case series and review of clinical presentation, diagnosis and management

Primary Cutaneous Endometriosis of Umbilicus

“Umbilical mass”: a case of primary umbilical endometriosis and literature review

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