Primary tumors and tumor-like lesions of the clavicle

Abstract

Fifty eight patients seen at Memorial Sloan-Kettering Cancer Center over a 50-year period were reviewed for lesions of the clavicle. A variety of malignant neoplasms, benign neoplasms, and tumor-like lesions were seen. There were 30 malignant neoplasms, the commonest of which were plasmacytomas, osteosarcomas, and Ewing sarcomas. There were five postradiation sarcomas. An unusual granulocytic sarcoma with dense sclerosis was described. Among the benign lesions were two osteochondromas, two hemangiomas, and a giant cell tumor secondary to Paget disease. The tumor-like lesions included six aneurysmal bone cysts and five eosinophilic granulomas. There were two patients with chronic sclerosing osteomyelitis and one each with sternocostoclavicular hyperostosis (Sonozaki syndrome) and condensing osteitis. An unusually large lesion of pseudogout and a large brown tumor were also included in the series.

Primary tumours and tumorous lesions of clavicle

“…The commonest histological diagnosis of clavicular tumours has been variously reported as myeloma [14] or osteosarcoma [16]. In our series, however, Ewing's sarcoma was the most common histological diagnosis.…”

“…The most commonly reported site of involvement of the clavicle is the acromial end, and tumours of the diaphyseal region are rare [7,16]. Our series, however, had an equal distribution of tumours in all areas of the bone.…”

“…That a majority of tumours of the clavicle are malignant is a fact reflected in many of the previous reports [14,16].…”

A 16-year-old Girl With Pain and Swelling in the Medial Clavicle

“…The shoulder girdle is the third most common site of primary bone tumors; however, clavicular tumors are rare, accounting for only 5% to 6% of shoulder girdle tumors [6,13]. Smith et al [13] reported their series of 58 clavicle tumors, 28 of which were benign.…”

“…Smith et al [13] reported their series of 58 clavicle tumors, 28 of which were benign. Osteochondroma, hemangioma, giant cell tumor, aneurysmal bone cyst, eosinophilic granuloma, fibrous dysplasia, simple cyst, and brown tumor of hyperparathyroidism were the benign tumors reported in the clavicle.…”