Primary tuberculosis of the thyroid gland: a case report

Kataria, Sant Parkash; Tanwar, Parul; Singh, Sukhbir; Kumar, Sanjay

doi:10.1016/s2221-1691(12)60240-8

Cited by 32 publications

(34 citation statements)

References 4 publications

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“…Tuberculosis of the thyroid gland is rare [1][2][3][4]. Thyroid is perceived to be an organ that is resistant to tuberculosis infection as it has a rich blood supply, high Iodine content and contains colloid which is bactericidal.…”

Section: Discussionmentioning

confidence: 99%

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Tuberculosis of Thyroid Gland in a Pediatric Patient

Popli¹,

Popli²

2018

MICR

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Tuberculosis of thyroid gland is rare. It is a rare pathology even in countries where tuberculosis is endemic. Here, we present a case of thyroid gland tuberculosis with no evidence of pulmonary tuberculosis in a three-year-old girl. The patient presented with a midline swelling which was diagnosed to be thyroglossal cyst clinically. Ultrasound imaging not only helped in proper localization of the pathology but also helped in reconsidering the diagnosis made clinically.

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Section: Discussionmentioning

confidence: 99%

“…Tuberculosis of the thyroid gland is rare [1][2][3][4]. As a result, when a patient presents with diffuse thyroid enlargement, solitary nodule or a midline swelling, tubercular etiology is never the first diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Tuberculosis of Thyroid Gland in a Pediatric Patient

Popli¹,

Popli²

2018

MICR

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“…Certain tissue in our body is resistant to tuberculosis including thyroid, cardiac muscle, skeletal muscle, and pancreas [5]. Thyroid gland is known to resist the infection but exact reason remains unclear.…”

Section: Discussionmentioning

confidence: 99%

Unusual Presentation of Tuberculous Thyroid Abscess in a Background of Hashimoto’s Thyroiditis in a Chronic Hepatitis B Carrier

Kandhasamy

Kumar

Sangwan

et al. 2016

Case Reports in Surgery

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Tuberculosis of thyroid gland is a very rare disease. It has variable presentations and may be sometimes associated with autoimmune thyroiditis. We report a case of 45-year-old male, with left sided painless neck swelling, with a purulent discharging sinus over it associated with night sweats and loss of appetite. Thyroid imaging disclosed heterogeneous enhancement of left lobe of thyroid gland with internal vascularity and coarse calcifications. Core needle biopsy revealed caseous necrosis and AFB positivity. Patient had thyroid peroxidase antibody and thyroglobulin antibody positivity and the rest of thyroid function tests were normal. Patient had positive Mantoux test, hepatitis B surface Ag, and low viral DNA. The patient was diagnosed as being a case of tuberculous abscess of thyroid gland and was put on antitubercular therapy for 2 months. Patient subsequently underwent left hemithyroidectomy when there was no response. Histopathological examination revealed tuberculosis of thyroid gland. A final diagnosis of tuberculous abscess of thyroid gland in a background of Hashimoto's thyroiditis in a chronic HBV carrier was made. Therefore, although rare tuberculosis of thyroid should be kept in mind as a differential diagnosis of thyroid swelling.

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“…Factors such as the thyroid capsule, high iodine levels within the gland, bactericidal action of the colloid, antitubercular action of thyroid hormones and the abundant lymphatic and vascular supply to the thyroid gland may explain why primary TB at this site is seldom encountered 8. Thyroid status may also play a role; it has been suggested that in hyperthyroidism an increase in the physiological activity of phagocytes may result in destruction of the mycobacteria 8…”

Section: Discussionmentioning

confidence: 99%

Primary tuberculosis of the thyroid gland: an unexpected cause of thyrotoxicosis

2014

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We describe a 38-year-old Indian man who presented with a 2-week history of fever, night sweats and neck swelling who was found to be clinically thyrotoxic with a nodular goitre, tachycardia and high fever. Biochemical investigation revealed hyperthyroidism in association with deranged liver function tests and raised inflammatory markers. Ultrasound and CT scans of the neck revealed multinodular thyroid enlargement. He was considered most likely to have an acute infectious thyroiditis with a differential diagnosis of a toxic multinodular goitre and was started on carbimazole and antibiotics. He underwent fine needle aspiration of the thyroid which revealed necrotic cells and acid-fast bacilli, confirming a diagnosis of primary tuberculosis (TB) of the thyroid gland with no evidence of any other organ involvement on systemic imaging. He was started on TB therapy for 6 months and discharged with outpatient follow-up. Symptoms and biochemical markers subsequently resolved.

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Primary tuberculosis of the thyroid gland: a case report

Cited by 32 publications

References 4 publications

Tuberculosis of Thyroid Gland in a Pediatric Patient

Tuberculosis of Thyroid Gland in a Pediatric Patient

Unusual Presentation of Tuberculous Thyroid Abscess in a Background of Hashimoto’s Thyroiditis in a Chronic Hepatitis B Carrier

Primary tuberculosis of the thyroid gland: an unexpected cause of thyrotoxicosis

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