Primary Testicular Osteosarcoma – A rare case

Ranawaka, R.A.A.U.; Siriweera, E. H.

doi:10.4038/jdp.v12i2.7743

Cited by 2 publications

(3 citation statements)

References 6 publications

(10 reference statements)

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“…c. Immunohistochemistry features i. Positive staining: Strong cytoplasmic positivity for Vimentin [6].…”

Section: Treatmentmentioning

confidence: 99%

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Primary Osteosarcoma of Testis and Para-Testicular Tissues: A Review and Update of the Literature

Venyo

2019

AUN

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It has been stated that genitourinary sarcomas are not common in adults and that they had been estimated at less than 2.7% of all sarcomas. [1-2] It had also been iterated that extra-osseous paratesticular soft tissue osteosarcoma is an extremely uncommon type of malignant tumor. Hong R, et al. [3] stated that due to the rarity of para-testicular osteosarcoma; its histogenesis; treatment; and as well as its specific survival rates were not available.Osteosarcoma of the testis refers to a testicular tumor that is composed of pure osteoid forming malignant cells with no skeletal origin. Gordetsky J [4] Due to the extreme rarity of primary and metastatic osteosarcomas of the testis and the scrotal contents; it would be envisaged that majority of clinicians globally would not be familiar with the presentation; diagnosis; treatment and biological behaviour of the disease. The ensuing article on primary osteosarcoma of testis and para-testicular tissues: a review and update of the Literature is divided into two parts: (A) Overview and (B) Miscellaneous narrations; summations; and discussions related to case reports; case series; and studies related to osteosarcomas of the testis and para-testicular tissues. AimTo review and update the literature on primary osteosarcomas of the testis and Para testicular tissues. MethodInternet data bases were searched including Google; Google

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“…c. Immunohistochemistry features i. Positive staining: Strong cytoplasmic positivity for Vimentin [6].…”

Section: Treatmentmentioning

confidence: 99%

“…Figure 1:The gross appearance of the resected specimen showing solid tan to white tumor in the testis (Small Arrow) and the tumor mass in the spermatic cord (Long Arrow)[6].…”

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confidence: 99%

Primary Osteosarcoma of Testis and Para-Testicular Tissues: A Review and Update of the Literature

Venyo

2019

AUN

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“…3 Extra skeletal osteosarcoma of the paratesticular structures is extremely rare and to our knowledge, the present patient represents the fourth reported case of a primary extra skeletal osteosarcoma of the scrotum. 4 The SAT B2 expression helps to distinguish osteoblastic differentiation from their mimickers. 1 It proved to be a valuable reliable marker in differentiating extraskeletal osteosarcomas from other paratesticular sarcomas arising in the scrotum wall.…”

Section: Introductionmentioning

confidence: 99%

SAT B2 a novel diagnostic adjunct in a rare presentation of extra skeletal osteosarcoma of scrotum

Sharma¹,

Kaler²

2020

JDPO

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SATB2 is a nuclear protein that plays a critical role in osteoblast lineage commitment. Diagnosing extra skeletal osteosarcomas at rare sites can be quite challenging as it might mimic hyalinized stroma. The utility of SATB2 expression in osteosarcomas and other bone and soft tissue tumours is an useful adjunct to histopathology in diagnosing these rare lesions. A 69 year old male, presented with scrotal swelling since 8 months. He underwent left sided orchidectomy because of the clinical suspicion of malignancy. Macroscopy revealed a solid mass in the para testicular tissue with no involvement of the testicular tissue. Cut surface is whitish, firm and homogenous. Microscopy showed malignant soft tissue tumor with areas showing osteoid differentiation and SAT B2 helped in confirmation of diagnosis by highlighting the osteoblastic nature of cells. Hence a diagnosis of Primary extra skeletal paratesticular osteosarcomas was made.

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Primary Testicular Osteosarcoma – A rare case

Cited by 2 publications

References 6 publications

Primary Osteosarcoma of Testis and Para-Testicular Tissues: A Review and Update of the Literature

Primary Osteosarcoma of Testis and Para-Testicular Tissues: A Review and Update of the Literature

SAT B2 a novel diagnostic adjunct in a rare presentation of extra skeletal osteosarcoma of scrotum

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