PRIMARY T-CELL LYMPHOMA OF THE BRAIN IN CHILDREN: A Case Report and Literature Review

Alghamdi, Hanan M.; Sabbah, Rajeh; Martin, Justin M.; Patay, Zoltán

doi:10.1080/088800100276343

Cited by 12 publications

(7 citation statements)

References 4 publications

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“…The family gave a concentrated fenugreek extract (about 8 g fenugreek seeds per day) without medical consultation for 6 months. MRI of the brain after six months showed complete remission which observed for 11 years [91]. Apoptosis induced by fenugreek was described in many different tumor cell lines: colon, osteosarcoma, leukemia, breast, and liver [90,92].…”

Section: Cyclitols and Carcinogenesismentioning

confidence: 99%

The Healing-Promoting Properties of Selected Cyclitols—A Review

et al. 2018

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Introduction: Myo-inositol and its derivatives cyclitols play an important role in the processes of cell regulation, signal transduction, osmoregulation, and ion channel physiology, and are a component of the cell membrane. Free cyclitols present in food or released during the degradation of galactosyl cyclitols by bacteria (in digestive tract) show some physiological benefits. Aim: The aim of this paper is to present and analyze the documented data about curative and healing properties of cyclitols. Results and discussion: Cyclitols are well known compounds in the treatment of an accompanied diabetes insulin resistance, and also obesity and polycystic ovarian syndrome. d-chiro-Inositol deficiency exacerbates insulin resistance in the liver, muscles, and fat, while depletion of myo-inositol results in the development of diabetic complications. Cyclitols are successfully applied in treatment of polycystic ovarian syndrome, simultaneous are observed effective reducing of BMI, improving the hormonal profile, and increasing fertility. Moreover, cyclitols have anti-atherogenic, anti-oxidative, anti-inflammatory, and anti-cancer properties. Conclusion: The properties of cyclitols may be a good therapeutic option in the reduction of metabolically induced inflammation. Due to well drugs tolerance and low toxicity of these compounds, cyclitols are recommend for pregnant women and also for children. Another advantage is their widespread presence and easy availability, which encourages their use in medicine.

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Section: Cyclitols and Carcinogenesismentioning

confidence: 99%

The Healing-Promoting Properties of Selected Cyclitols—A Review

et al. 2018

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“…In the other three children the diagnostic method was not reported. The DLBCL is the most common subtype (13 [30%] of 43), followed by ALCL (21%; seven T-cell and two null-cell tumors), lymphoblastic lymphoma (16%; five precursor-B and two Tcell lesions 6,78 ), Burkitt (12%), histiocytic (5%, confirmed by immunohistochemical findings), and other (6%) lesions. Histological findings were not reported in 10% of cases.…”

Section: Pathological Featuresmentioning

confidence: 99%

Primary central nervous system lymphoma in children

Abla¹,

Weitzman²

2006

FOC

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✓ Primary central nervous system lymphoma (PCNSL) is a very rare brain tumor in children, and the optimal management and prognosis of such patients have yet to be defined. In this study, the incidence rate, clinical features, diagnosis, and treatment of childhood PCNSL are reviewed. Except for human immunodeficiency virus–related PCNSL, the prognosis for patients with this tumor type is significantly better in children than in adults. In the absence of prospective studies, it is very difficult to determine the true incidence and the best therapeutic strategy for this rare entity. The majority of children with PCNSL, however, can achieve long-term remissions with intensive chemotherapy alone (an estimated 70% 5-year event-free survival rate), and cranial irradiation can be reserved for relapse of the disease. Further progress in the management of childhood PCNSL will require prospective multinational studies.

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“…8 Few cases of children with primary T-cell lymphomas of the brain were described, though none of them were classified as mature T-cell lymphoma, unspecified. 9,10 In general, most of PCNSL are of B-cell lineage. Thus, T-cell lineage PCNSLs are poorly defined.…”

Section: Discussionmentioning

confidence: 99%

First Case Report of a Peripheral T-cell Lymphoma, not Otherwise Specified, of the Central Nervous System in a Child

Lueth

Stein²,

Spors³

et al. 2012

Journal of Pediatric Hematology/Oncology

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We report on the first pediatric patient with a localized primary peripheral T-cell lymphoma, not otherwise specified, of the central nervous system (CNS). The solid lesion that was enhanced in magnetic resonance images of the left precentral region was totally resected. The histopathology revealed a peripheral T-cell lymphoma, not otherwise specified. Staging procedures showed that the lesion was confined to the CNS. Without any further therapy, the patient still remains in complete remission 6 years after diagnosis. Thus, we conclude that a peripheral T-cell lymphoma, not otherwise specified, of the CNS can occur in children. In the case presented here, complete resection sufficed.

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PRIMARY T-CELL LYMPHOMA OF THE BRAIN IN CHILDREN: A Case Report and Literature Review

Cited by 12 publications

References 4 publications

The Healing-Promoting Properties of Selected Cyclitols—A Review

The Healing-Promoting Properties of Selected Cyclitols—A Review

Primary central nervous system lymphoma in children

First Case Report of a Peripheral T-cell Lymphoma, not Otherwise Specified, of the Central Nervous System in a Child

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