Primary Synovial Sarcoma of the Nasopharynx in a Case—Case Report

Abstract

Synovial sarcoma (SS) is a rare malignant tumor with bidirectional differentiation potential in epithelial and mesenchymal tissues and is a more chemosensitive subtype of soft tissue sarcoma. It occurs around the synovial soft tissues of large joints of the extremities and rarely in the nasopharynx. We present a young man with recurrent left-sided nasal congestion with nosebleeds, confirmed by immunohistochemistry and cytogenetic examination as SS. SS is easily misdiagnosed, and the tumor should be considered in the differential diagnosis, with surgery combined with radiotherapy as the primary treatment option.