Primary stroke prevention worldwide: translating evidence into action

Owolabi, Mayowa; Thrift, Amanda G; Mahal, Ajay; Ishida, Marie; Martins, Sony; Johnson, Walter D.; Pandian, Jeyaraj Durai; Abd‐Allah, Foad; Yaria, Joseph; Phan, Hoang; Roth, Greg; Gall, Seana; Beare, Richard; Phan, Thanh G.; Mikulík, Robert; Akinyemi, Rufus; Norrving, Bo; Brainin, Michael; Feigin, Valery

doi:10.1016/s2468-2667(21)00230-9

Cited by 183 publications

(76 citation statements)

References 70 publications

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“…Such a high expense may increase the burden of cancer care and treatment that may be beyond the affordable range for patients and family members. The patients may feel a severe economic burden, which may lead to emotional and spiritual discomfort [ 9 , 10 ]. The cancer patients often acquire multiple chronic conditions, requiring extensive and expensive palliative care services [ 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Evolution of Oncology and Palliative Nursing in Meeting the Changing Landscape of Cancer Care

Zhou

2022

Journal of Healthcare Engineering

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Nursing is a vital health profession. In almost all clinical and hospital settings, nurses offer primary palliative care. Nurses are recognized for their strong philosophy of care for a wide spectrum of disorders. No matter the sickness, condition, or clinical situation, palliative care is considered essential in nursing practice. Palliative care nursing is the provision of palliative care services to cancer patients and their families, regardless of whether cancer can be cured or not. A large body of evidence shows that early palliative care nursing integration improves the quality of life and survival of cancer patients. Due to the intricacy of cancer, the landscape of cancer care is shifting. Cancer is a life-threatening disease with a high mortality rate. Oncology nurses’ skills and experience are vital in providing specialized patient care and fulfilling the needs of patients and their families. The current study examines the shifting environment of palliative care nursing in oncology. However, new palliative care nursing approaches are required to adapt to the evolving cancer scenario.

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Section: Introductionmentioning

confidence: 99%

Evolution of Oncology and Palliative Nursing in Meeting the Changing Landscape of Cancer Care

Zhou

2022

Journal of Healthcare Engineering

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“…According to the World Stroke Organisation, such a strategy should include, in addition to a polypill-type approach, population-wide policy strategies to reduce exposure to risk factors (eg, air pollution, smoking cessation, salt reduction), as well as motivational health apps to reduce lifestyle risk factors and other interventional preventive measures to control behavioral risk factors. 29,30…”

Section: Chances and Challengesmentioning

confidence: 99%

Polypill: Benefits Seen for Stroke and Other Outcomes

Brainin

Teuschl

Martins

2022

Stroke

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A polypill-type strategy for primary prevention was first published at the turn of the century and advised that a multi-ingredient pill applied to an adult population would prevent up to 80% of cardiovascular and stroke events. Such a pill should contain small doses of antihypertensives, lipid-lowering drugs, and some nutrients. The startling increase of the global stroke burden has led to a revival of this concept and the propagation of a population-based prevention strategy. Recent cardiovascular fixed-dose combination trials have shown a significant effect in reducing not only blood pressure and cholesterol levels but also in reducing cardiovascular and stroke events. In most of the studies, the study population was for secondary prevention and the total number of strokes was small. Nevertheless, it is now clear that a large proportion of primary prevention must take this path. It is especially promising when combined with community health workers interventions for modifying risk behavior. While a polypill-type approach seems most efficacious in underserved regions of high-income countries as well as in low- and middle-income countries, it seems to have a large overall effect in spite of some problems with nonadherence or potential side effects. It should be available and affordable for large target populations. Larger phase 4 studies are under way.

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“…On a larger scale, more effective HIC–LMIC and LMIC–LMIC partnerships could increase resources and build capacity. To improve stroke surveillance, prevention, acute care and rehabilitation, the World Health Organization (WHO)–World Stroke Organization–Lancet Commission on stroke is developing the global Stroke Control, Observatory, and Reduction Ecosystem (gSCORE) 10 . This ecosystem will harness and leverage global resources, including the WHO and United Nations non-communicable disease control plan and the WHO intersectoral global action plan against neurological diseases.…”

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confidence: 99%