Primary Splenic Lymphoma Complicated by Hematemesis and Gastric Erosion

Bird, Mark A.; Amjadi, Darius; Behrns, Kevin E.

doi:10.1097/00007611-200295080-00034

Cited by 24 publications

(15 citation statements)

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“…The clinical presentation of our patient coupled with the absence of any significant past medical history or evidence of endocarditis helped to exclude other differential diagnoses such as necrotising splenic abscess. In previously described cases the spleen was shown to be heterogenous with parenchymal masses containing air, similar to our case 8 9. The fistulous tract has been outlined with oral contrast7 in some cases.…”

Section: Discussionsupporting

confidence: 84%

“…These characteristics were also present in our patient. Furthermore, our patient's admission was complicated with haematemesis, which has been the clinical presentation of other gastrosplenic fistulas 6 8…”

Section: Discussionmentioning

confidence: 87%

“…To our knowledge, there have been only six reported cases of spontaneous gastrosplenic fistula associated with a primary splenic lymphoma 5 7–9 16. We report the seventh case of a spontaneous gastrosplenic fistula from a primary splenic non-Hodgkin's lymphoma.…”

Section: Discussionmentioning

confidence: 99%

“…Patients are at risk of haematemesis due to the risk of invasion into adjacent vasculature, specifically the gastric and splenic vessels. Treatment can also be supportive and in life threatening blood loss interventional radiology in the form of splenic artery embolisation8 has been described. Surgery in our patient would have been a huge undertaking with associated high mortality in view of the size of the lesion and multiple adjacent structures involved.…”

Section: Discussionmentioning

confidence: 99%

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Spontaneous gastrosplenic fistula secondary to primary splenic lymphoma

Khan¹,

Vessal

McKimm

et al. 2010

Case Reports

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A gastrosplenic fistula is a rare complication of gastric and splenic lymphomas which can occur spontaneously or secondary to chemotherapy. We report a case of a spontaneous gastrosplenic fistula secondary to a diffuse splenic large B cell lymphoma in a previously well 43-year-old patient. CT imaging demonstrated the fistula, which was subsequently managed with chemotherapy. The clinical management of this rare condition is discussed with a review of the literature.

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Section: Discussionsupporting

confidence: 84%

Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Spontaneous gastrosplenic fistula secondary to primary splenic lymphoma

Khan¹,

Vessal

McKimm

et al. 2010

Case Reports

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“…So, line of treatment of such SLs should be same as DLBCLS[33]. Splenic form of the micronodular T-cell/histiocyte-rich DLBCL subtype presents with micronodules in the spleen with involvement of bone marrow or other extranodal sites[34,35]. …”

Section: Diagnostic and Therapeutic Splenectomymentioning

confidence: 99%

Primary splenic lymphoma: Current diagnostic trends

Ingle¹,

Hinge²

2016

WJCC

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The primary splenic lymphoma is extremely uncommon, can present with grave complications like hypersplenism and splenic rupture. In view of vague clinical presentation, it is difficult to arrive at the diagnosis. In such circumstances, histopathological diagnosis is very important. A precise diagnosis can only be made on histopathology and confirmed on immunohistochemistry.Emergency splenectomy is preferred as an effective therapeutic and diagnostic tool in cases with giant splenomegaly. Core biopsy is usually not advised due to a high risk of post-core biopsy complications in view of its high vascularity and fragility. Aim behind highlighting the topic is to specify that core biopsy/ fine needle aspiration cytology can be used as an effective diagnostic tool to arrive at correct diagnosis to prevent untoward complications related to disease and treatment. Anticoagulation therapy is vital after splenectomy to avoid portal splenic vein thrombosis.

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