Primary spinal melanoma: illustrative case

House, Hanna; Archer, Jacob; Bradbury, Jamie

doi:10.3171/case21542

Cited by 3 publications

(3 citation statements)

References 11 publications

(19 reference statements)

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“…Despite cardiopulmonary resuscitation, the patient passed away a month after surgery. Patients diagnosed with metastatic cutaneous melanomas normally have a 1-year survival rate, but initial spinal cord melanomas have a 6-year and 7-month survival rate [ 7 , 8 ]. However, our patient had been complaining of anterior cervical spine swelling for 2 years.…”

Section: Discussionmentioning

confidence: 99%

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Primary malignant melanoma, an atypical presentation in the cervical spine: a case report

Kamabu,

Kataka,

Vivalya

et al. 2023

J Med Case Reports

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Background Few studies have documented the occurrence of melanoma in the cervical spine. Of all malignant melanoma cases, 1% are primary melanoma of the central nervous system, which makes it extremely uncommon and nonspecific. We aim to report a case of the uncommon presentation of primary melanoma in the cervical spine. Case presentation The patient was a 59-year-old Muganda male who presented with a 2-year history of anterior neck swelling as well as severe pain and a tingling sensation in the left shoulder and arm, which worsened in the recent 6 months. He developed weakness and paresthesia in the upper left arm and progressive gait disturbance of the left leg. A physical examination revealed masses in the left cervical and right submandibular region. Additionally, the upper and lower left extremities revealed hemiparesis and hemihypoesthesia. A magnetic resonance imaging scan showed a hyperintense lesion on TIWI and another hypointense lesion on T2WI, originating from the cervical spine and involving the vertebral bodies and paravertebral soft tissues. The patient underwent surgery, a black tumor was extracted, and histology revealed the tumor to be malignant melanoma. The patient died within 1 month after the diagnosis and surgery. Conclusion This case is presented to highlight the significance and challenges associated with making a pre- and postoperative diagnosis of primary cervical melanoma with atypical radiological characteristics. Patients with extradural lesions that show hyperintensity on T1-weighted images and hypointensity on T2-weighted images should have spinal melanoma examined as a possible differential diagnosis.

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Section: Discussionmentioning

confidence: 99%

“…There has not been much investigation into the treatment and prognosis of primary spinal cord melanoma. Resection has been proposed as the preferred treatment for primary spinal melanomas [ 7 , 15 ]. Subtotal resection was the second most popular method used for resection after gross total resection (GTR) [ 15 ].…”

Section: Discussionmentioning

confidence: 99%

Primary malignant melanoma, an atypical presentation in the cervical spine: a case report

Kamabu,

Kataka,

Vivalya

et al. 2023

J Med Case Reports

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“…The present case meets the criteria with the following: (1) absence of malignant melanoma outside of CNS and (2) histopathologic testing for melanoma [26,27]. While patients with primary malignant melanoma have experienced extended survival time and/or cure, patients with metastatic melanoma of the CNS have had a significantly diminished prognosis [2,25,[28][29][30][31][32][33][34]. On average, individuals with PSM live six years longer than patients with metastatic melanoma in the CNS [31].…”

Section: Workup Of Primary Spinal Melanomamentioning

confidence: 99%

Surgical Management of Primary Thoracic Epidural Melanoma

Khalilullah,

Mignucci-Jiménez,

Huffman

et al. 2024

Cureus

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In this study, we reported one of the first cases where a rare robotic-assisted platform with neuronavigation technology and carbon-fiber-polyetheretherketone (CF/PEEK) screws is employed to surgically treat multilevel thoracic primary spinal epidural melanoma. A 67-year-old male presented with left upper thoracic pain. His magnetic resonance imaging (MRI) of the thoracic spine revealed a dumbbell-shaped left epidural mass at the T2-3 level. Partial resection was performed due to tumor growth into the vertebral bodies and patient discretion for minimal surgery. The patient’s neurological conditions improved postoperatively, with reduced reported symptoms of pain and numbness. Postoperative imaging showed evidence of appropriate spinal stabilization. Patient underwent stereotactic body radiation therapy (SBRT), and no adverse events were reported. This case reflects one of the first examples of treating thoracic epidural melanoma with the use of robotic-assisted navigation. Further prospective studies are needed to determine the efficacy of robot-assisted navigation for patients with primary spinal malignant melanoma which may open the possibility of surgery to once presumed non-operative patients.

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Understanding citizens' perception of channels for participating in administration based on their motivation in an authoritarian regime: The case of Gaza Province, Mozambique

Sitoe,

Lim

2023

J of Intl Development

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Studies aiming to evaluate the effectiveness of channels for participating in administration have been conducted mainly in democratic, developed countries. However, outcomes from those settings may not apply to developing or less developed countries where democracy has yet to be consolidated. In Mozambique, which has an authoritarian regime, the effectiveness of participatory channels from the public point of view remains unexplored. Therefore, based on participants' motives for participation, this study empirically examines citizens' perception of channels for participating in administration with specific reference to Gaza Province and suggests that policy makers and administrators design participation channels for local governments to ensure and protect citizens' authentic participation in administration.

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Primary spinal melanoma: illustrative case

Cited by 3 publications

References 11 publications

Primary malignant melanoma, an atypical presentation in the cervical spine: a case report

Primary malignant melanoma, an atypical presentation in the cervical spine: a case report

Surgical Management of Primary Thoracic Epidural Melanoma

Understanding citizens' perception of channels for participating in administration based on their motivation in an authoritarian regime: The case of Gaza Province, Mozambique

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