Primary Spinal Cord Tumors

Munns, Justin; Park, Daniel K.; Deutsch, Harel; Singh, Kern

doi:10.1097/01.css.0000350573.22077.61

Cited by 1 publication

(1 citation statement)

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“…Extramedullary tumors are formed from peripheral nerve roots or their membranes and are not part of the central nervous system (CNS), whereas intramedullary tumors originate from glial and support cells of the spinal cord. In this meta-analysis, the term “PSCT” will be used to designate all intramedullary and extramedullary (intradural and extradural) pathologies within the spinal canal arising from glial cells and supporting cells [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Laminoplasty versus Laminectomy in the Treatment of Primary Spinal Cord Tumors in Adult Patients: A Systematic Review and Meta-analysis of Observational Studies

et al. 2023

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The present systematic review and meta-analysis was conducted to compare the safety and efficacy of the two approaches for primary spinal cord tumors (PSCTs) in adult patients (laminoplasty [LP] vs. laminectomy [LE]). LE is one of the most common procedures for PSCTs. Despite advantages of LP, it is not yet widely used in the neurosurgical community worldwide. The efficacy of LP vs. LE remains controversial. Adult patients over 18 years of age with PSCT at the level of the cervical, thoracic, and lumbar spine were included in the study. A literature search was performed in MEDLINE via PubMed, EMBASE, The Cochrane Library, and Google Scholar up to December 2021. Operation time, hospital stay, complications, and incidence of postoperative spinal deformity (kyphosis or scoliosis were extracted. A total of seven retrospective observational studies with 540 patients were included. There were no significant differences between LP and LE group in operation time (p=0.25) and complications (p=0.48). The LE group showed larger postoperative spinal deformity rate than the LP group (odds ratio, 0.47; 95% confidence interval [CI], 0.27−0.84; p=0.01). The LP group had a shorter hospital stay (standardized mean differences, −0.68; 95% CI, −1.03 to −0.34; p=0.0001) than the LE group. Both LP and LE have comparable operative times and total complications in the treatment of PSCT. LP was superior to LE in hospital stay and postoperative spinal deformity rate. However, these findings are limited by the very low quality of the available evidence. Randomized controlled trials are needed for further comparison.

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Section: Introductionmentioning

confidence: 99%