Primary small cell neuroendocrine carcinoma of the urinary bladder

Chilari, Geetha Aravind; Prabhala, Shailaja; Gutta, Srinivas; Erukkambattu, Jayashankar

doi:10.4103/2277-8632.158604

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“…Urothelial carcinoma is the most common malignancy found in urinary bladder, but rare neoplasms like neuroendocrine tumors (NETs) do occur at this location. [12] NETs are epithelial tumors with neuroendocrine differentiation and can be found in most organs in the human body including the urinary bladder. In bladder, NETs are usually found intermixed with urothelial carcinoma and its variants.…”

Section: Introductionmentioning

confidence: 99%

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Role of immunohistochemistry in diagnosis of a rare bladder tumor

2019

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Neuroendocrine tumors (NETs) are commonly located in the respiratory and gastrointestinal tract; however, these tumors can rarely be found in the urinary bladder. NETs comprise <1% of all bladder tumors; usually intermixed with urothelial carcinoma and its variants. We report a case of primary neuroendocrine carcinoma of urinary bladder in an adult female with a history of smoking and hematuria. The present case highlights the importance of immunohistochemistry in arriving at an accurate diagnosis and thereby differentiating this tumor from other clinical mimics.

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Section: Introductionmentioning

confidence: 99%

“…Primary neuroendocrine carcinomas of the urinary bladder account for <1% of all bladder tumors. [123] It was first reported by Cramer in 1981. [2] The most common presentation is hematuria.…”

Section: Introductionmentioning

confidence: 99%