Primary septic arthritis of the knee caused by Neisseria meningitidis serogroup B in an elderly patient. Case report and review of the literature

Abstract

Purpose: Primary meningococcal arthritis (PMA) represents an uncommon clinical presentation of meningococcal infection, mainly reported among young people. Herein, a case of PMA of the knee in an elderly patient is described.Case presentation: On January 2022, an 87-year-old patient arrived at hospital with continuous fever persisting for three days and a picture of joint pain, swelling, redness, and warmth of her left knee. An arthrocentesis was promptly performed and the inoculated synovial uid turned positive with numerous Gram-negative diplococci at the microscopic examination. The BioFire® FilmArray®Meningitis/Encephalitis (ME) Panel (bioMérieux) quickly con rmed the presence of Neisseria meningitidis. The meningococcal isolate belonged to the serogroup B (MenB), Sequence type (ST)-162/ clonal complex (cc)162.Two grams of ceftriaxone twice a day were administered for 21 days; than cefditoren pivoxil 400 mg twice a day for further 6 weeks after discharge.

Genome-wide identification and oxacillinase OXA distribution characteristics of Acinetobacter spp. based on a global database

“…With the rapid development of matrix-associated laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) and whole genome sequencing (WGS) technology, the current classification of Acinetobacter spp. urgently needs to be updated, since different species have been reported to cause different infections and show different drug resistance characteristics ( Antunes et al, 2014 ; Zajmi et al, 2022 ; Longo et al, 2023 ).…”