Primary SARS‐CoV‐2 infection in children and adults results in similar Fc‐mediated antibody effector function patterns
Anne T Gelderloos,
Anke J Lakerveld,
Rutger M Schepp
et al.
Abstract:ObjectivesIncreasing evidence suggests that Fc‐mediated antibody effector functions have an important role in protection against respiratory viruses, including SARS‐CoV‐2. However, limited data are available on the potential differences in the development, heterogeneity and durability of these responses in children compared to adults.MethodsHere, we assessed the development of spike S1‐specific serum antibody‐dependent cellular phagocytosis (ADCP), complement deposition (ADCD) and natural killer cell activatio… Show more
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