Primary Sarcoma of the Bronchus and Lung

Hochberg, Lew A.; Crastnopol, Philip

doi:10.1001/archsurg.1956.01280010076012

Cited by 40 publications

(3 citation statements)

References 34 publications

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“… 3 Hochberg and Crastnopol analyzed 77 patients with primary pulmonary sarcoma, and the most common variants observed were fibrosarcoma and leiomyosarcoma, with liposarcoma seen in only 2 patients. 6 The Table presents a review of the literature of primary pulmonary PLS, as well as the details of this case.…”

Section: Discussionmentioning

confidence: 99%

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Rare Case of Primary Pulmonary Pleomorphic Liposarcoma Treated With Multimodal Therapy

Dey¹,

Khosla²,

Chatterjee³

et al. 2021

TOJ

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Background: Pleomorphic liposarcoma (PLS) is a very rare type of primary pulmonary sarcoma. Clinical data about these tumors are limited, and optimal treatment has not yet been defined. Case Report: A 32-year-old male presented with pain and heaviness over the right chest. Contrast-enhanced computed tomography (CECT) of the chest showed a heterogeneous hypodense pleural-based mass and a mediastinal mass. The patient was treated with chemoradiotherapy, followed by excision and adjuvant chemotherapy. Seven months after completion of treatment, he presented with an abdominopelvic mass and soft tissue peritoneal deposits. The mass was resected, and second line chemotherapy resulted in a partial response. The patient was routinely followed. Six months after completion of the second round of chemotherapy, CECT showed multiple soft tissue deposits in the right lumbar region, right hemipelvis, and presacral region with no evidence of pulmonary disease. Chemotherapy elicited a partial response. Three years from the date of diagnosis, the patient was alive with stable disease. Conclusion: This case is unique because of the rare primary site of PLS presentation and the rare presentation of peritoneal metastasis. Citing such cases would help us to define adequate treatment protocols for this aggressive tumor.

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Section: Discussionmentioning

confidence: 99%

“… 8 Approximately 10% of all primary pulmonary liposarcomas are asymptomatic, which may be because of the expansile nature of the tumor rather than infiltration. 6 Also, because these tumors are slow growing, they often present as a large mass. The absence of any characteristic symptom further delays diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Rare Case of Primary Pulmonary Pleomorphic Liposarcoma Treated With Multimodal Therapy

Dey¹,

Khosla²,

Chatterjee³

et al. 2021

TOJ

View full text Add to dashboard Cite

show abstract

“…Very rarely Hodgkin's disease may start in the lung (Monahan 1965, Hochburg & Crastnopol 1956), and the lungs are frequently the sites of secondary deposits in advanced and fatal cases. Secondary pulmonary deposits may take the form of (a) a solitary nodule resembling a deposit of secondary carcinoma, (b) miliary nodules scattered throughout both lungs, (c) a large mass occupying the whole or the major part of a lobe which often undergoes central cavitation, (d) pleural plaques, and (e) very rarely nodular deposits in the walls of the large bronchi.…”

Section: Section Ofradiology 739mentioning

confidence: 99%