Primary retroperitoneal Merkel cell carcinoma: Case report and literature review

Quiroz-Sandoval, Osvaldo A.; Cuéllar-Hübbe, Mario; Lino-Silva, Leonardo S.; Salcedo-Hernández, Rosa Angélica; López-Basave, Horacio Noé; Padilla-Rosciano, Alejandro; León-Takahashi, Alberto M.; Herrera‐Gómez, Ángel

doi:10.1016/j.ijscr.2015.12.003

Cited by 6 publications

(5 citation statements)

References 31 publications

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“…Clinically the MCC appears typically like primary a cutaneous injury (75%), although it can make debut as a metastatic disease [7]. There are currently two possible explanations for what occurred in our patient.…”

Section: Discussionmentioning

confidence: 74%

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Atypical Presentation of Merkel Cells Carcinoma in Thigh. An Unusual Case

Limardo¹

2017

JOJCS

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Background:The Merkel Cells Carcinoma (MCC) is a neuroendocrine carcinoma of the skin. MCC within the lymph nodes in the absence of a primary site is rare and has only been reported sporadically.Case report: A male patient of 62 years old consults by right inguinal tumor. Lymphadenectomy is made and it informs carcinoma of cells of Merkel. Hidden primary tumor. After 20 months of follow up appears injury to nodular in internal face of right thigh interpreted like primary tumor. Resection is made. We discuss the disease, the diagnosis and the treatment of these tumors. Conclusion:The Merkel Cells Carcinoma (MCC) is a neuroendocrine carcinoma of the skin. MCC within the lymph nodes in the absence of a primary site is rare and has only been reported sporadically. Our case may represent a lymph node metastasis from an occult or regressed skin primary, but we cannot preclude the possibility of a primary nodal tumor. It is not known until today as it is "the best" therapeutic choice for these cases Keywords: Tumor of cells of Merkel; Carcinoma of cells of Merkel; Rare Tumors of soft parts .

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Section: Discussionmentioning

confidence: 74%

“…In the presence of a nodal Merkel cell tumor, an exhaustive clinico-radiologic search for a primary tumor must be carried out [7]. MRI of abdomen, pelvis and thighs is realized and Fibro colonoscopy was made in our patient.…”

Section: Discussionmentioning

confidence: 99%

Atypical Presentation of Merkel Cells Carcinoma in Thigh. An Unusual Case

Limardo¹

2017

JOJCS

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“…Siref et al reported a case of MCC presenting as a visceral malignancy where there were no cutaneous findings [19]. Quiroz-Sandoval et al reported a case of large retroperitoneal mass presenting as MCC, which was successfully excised [20]. As for our patient, she had neither personal nor family history of malignancy and presented with acute respiratory failure in the setting of pleural effusion with hilar mass and liver mass.…”

Section: Table 1: Immunobiological Markers Of MCCmentioning

confidence: 73%

A Primary Extracutaneous Presentation of Merkel Cell Carcinoma

Dalal¹,

Iqbal²,

Mahapatra³

et al. 2022

Cureus

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Merkel cell carcinoma (MCC) is a rare aggressive cutaneous neuroendocrine malignancy with a mortality rate of around 33%. The presence of advanced disease at the time of diagnosis is associated with poor prognosis. Twofold etiologies have been described in the pathogenesis of Merkel cell carcinoma: chronic exposure to ultraviolet (UV) light and Merkel cell polyomavirus (MCPvY). MCC usually affects sun-exposed skin areas, and the presence of cutaneous nodules is the hallmark of the disease. However, there have been case reports in the literature where the diagnosis of MCC was made in the absence of any cutaneous findings. We present a case report of Merkel cell carcinoma that is unique in its presentation because of the presence of pulmonary and hepatic nodules and the absence of cutaneous lesions.

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“…Only 13 cases [5][6][7][8][9][10][11][12][13][14][15][16][17] met the condition of having a retroperitoneal Merkel cell involvement without primary skin lesion, they are summarized in Table 1. Most of the cases had retroperitoneal nodal affection (7 cases) or pancreatic involvement (2 cases), with only 4 plus our case with a real retroperitoneal mass of unknown origin that could be classified as the main tumor [5][6][7][8].…”

Section: Literature Review Resultsmentioning

confidence: 99%

“…Most of the cases had retroperitoneal nodal affection (7 cases) or pancreatic involvement (2 cases), with only 4 plus our case with a real retroperitoneal mass of unknown origin that could be classified as the main tumor [5][6][7][8].…”

Section: Literature Review Resultsmentioning

confidence: 99%

Retroperitoneal Merkel Cell Carcinoma without Skin Involvement: Literature Review and One Case Experience

Sota¹,

Vila²,

Giménez³

et al. 2017

Ann Clin Lab Res

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Merkel cell carcinoma (MCC) is an uncommon neuroendocrine tumor that represents a small percentage of skin malignancies, with an aggressive behavior and survival rate at 5 years of 20% to 80%. Among the risk factors, we find Ultraviolet radiation, polyomavirus, other malignancies and immunosuppression.Most of the MCC are diagnosed over 59 years old, being more frequent in men. According to the literature, only 2% to 5% had no skin involvement. Among regions involved, head and neck are the most frequent, followed by limbs and lymph nodes.We described a case of MCC without skin involvement, atypically located in retroperitoneum and given the rarity of both circumstances, we also conducted a review of the reported cases of retroperitoneal MCC without skin tumor.Among retroperitoneal MCC without primary skin involvement, we found 13 reported cases, the average age of these patients was 66 years old, being female only one case. They were all diagnosed by computerized tomography (CT) or Positron emission tomographycomputed tomography (PET-CT). The size of the main mass was variable (15 cm to 3 cm) and selected treatments were chemotherapy, surgery and radiation therapy. Survival rate is unknown in most of them.

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Primary retroperitoneal Merkel cell carcinoma: Case report and literature review

Cited by 6 publications

References 31 publications

Atypical Presentation of Merkel Cells Carcinoma in Thigh. An Unusual Case

Atypical Presentation of Merkel Cells Carcinoma in Thigh. An Unusual Case

A Primary Extracutaneous Presentation of Merkel Cell Carcinoma

Retroperitoneal Merkel Cell Carcinoma without Skin Involvement: Literature Review and One Case Experience

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