Primary Retrobulbar and Intraocular Malignant Melanoma in a Cat

Siripoonsub, Jedsada; Chankow, Katriya; Lacharoje, Sitthichok; Rungsipipat, Anudep

doi:10.14737/journal.rjvp/2016/4.2.17.21

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…19 FROMS, previously termed 'pseudotumour' is a highly invasive neoplasm that often progresses from unilateral to bilateral disease and is poorly responsive to therapy. 3,18,19,22,[24][25][26][27][28][29][30][31] SCC can mimic FROMS. 22 Radiography appears insensitive for the detection of orbital bone pathology.…”

Section: Introductionmentioning

confidence: 99%

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Tumours involving the retrobulbar space in cats: 37 cases

Jones¹,

Cotterill

Drees

et al. 2022

Journal of Feline Medicine and Surgery

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Objectives The aim of this multicentre retrospective study was to describe the clinical presentation, imaging findings, diagnosis and outcomes of cats with retrobulbar neoplasia. Methods A total of 37 cats that were diagnosed with retrobulbar neoplasia and underwent advanced imaging were recruited from searches of the clinical records of two referral hospitals. All cats had neoplasia confirmed via cytology or histopathology. Data relating to the signalment, presentation, results of investigations, treatment and outcome were recorded. A review of imaging studies was performed where possible. Results In total, 23 cases (62%) were presented with respiratory signs. Exophthalmos was the most common ophthalmological examination finding, present in 18 cases (49%). Thirty-two cases (86%) had secondary extension of neoplasia to the retrobulbar space (most commonly from the nasal cavities), present in 20 cases (54%), of which 12 were lymphoma. In cases where contrast was administered, 28/35 (80%) had contrast-enhancing masses. Orbital extension was detected in 21 cases (57%), exophthalmos in 22 (59%), globe deformation in 12 (32%) and local lymphadenomegaly in 22 (61%). In total, 36 (97%) retrobulbar tumours were malignant. Thoracic imaging, where it was performed, was concerning for metastasis in 8/25 cases (31%), with abdominal imaging suggestive of metastasis in 5/12 (42%). The most common diagnosis was lymphoma with 19 cases (51%), with nasal lymphoma representing 12 of these, followed by carcinoma in 10 (27%). The median survival time, for cases where death was recorded, was 85 days (range 1–263 days). Conclusions and relevance To the authors’ knowledge, this is the largest study of neoplasia affecting the feline retrobulbar space. Retrobulbar tumours in cats are overwhelmingly malignant, and commonly due to secondary extension of tumours originating elsewhere. Lymphoma, particularly arising from the nasal cavities, was the most common cause. Cats presenting with signs suggestive of retrobulbar disease should be assessed for disease affecting any of the structures of the head.

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Section: Introductionmentioning

confidence: 99%

“…19 FROMS, previously termed ‘pseudotumour’ is a highly invasive neoplasm that often progresses from unilateral to bilateral disease and is poorly responsive to therapy. 3,18,19,22,24–31 SCC can mimic FROMS. 22…”

Section: Introductionmentioning

confidence: 99%

Tumours involving the retrobulbar space in cats: 37 cases

Jones¹,

Cotterill

Drees

et al. 2022

Journal of Feline Medicine and Surgery

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Melanoma uveal en un canino: un reporte de caso

Toro

Betancur

2019

Ces. Med. Vet. Zootec.

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En el presente reporte se expone el caso clínico de un canino macho Gran Danés Arlequín, el cual, presentó el ojo derecho opaco y muy rojo. En el examen oftalmológico presentó un cuadro agudo de uveítis, seguido por glaucoma y déficit visual; no reporta trauma físico o algún golpe contundente a nivel ocular. El diagnóstico definitivo fue melanoma uveal, confirmado por ecografía, citología e histopatología.

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Primary Retrobulbar and Intraocular Malignant Melanoma in a Cat

Cited by 2 publications

References 7 publications

Tumours involving the retrobulbar space in cats: 37 cases

Tumours involving the retrobulbar space in cats: 37 cases

Melanoma uveal en un canino: un reporte de caso

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