Primary Renal Malignant Fibrous Histiocytoma

Abstract

Primary renal malignant fibrous histiocytoma is a rare tumor of the kidney. We report an additional case noting, as other authors have, the similarity in clinical presentation with renal cell carcinoma. We also review the 23 documented cases of the international literature, emphasizing the current diagnostic approaches and therapeutic management.

Primary malignant fibrous histiocytoma of the kidney: report of a case and literature review

“…[26] The overall prognosis is poor, and the 5-year survival rate is less than 14%. [12] The present case demonstrated recurrence and metastases postoperatively within five and eight months, respectively, and despite polychemotherapy, the patient died of disease within the first postoperative year. …”

“…[4][5][6][7][8][9][10][11] The most frequent presenting symptoms are a palpable abdominal mass, fever, fatigue, weight loss, and gastrointestinal problems. [12] These symptoms are non-specific and usually appear late. Therefore, early diagnosis is difficult.…”

Pleomorphic undifferentiated sarcoma: A case of a giant renal mass

“…Initial plan should be total surgical excision, even though it is a tumor with high risk of local recurrence. 4 We performed radical nephrectomy without any tumor on the surgical margin, so the prognosis of our case was favorable.…”

A huge benign fibrous histiocytoma arising from the renal capsule: report of a case

“…It is difficult to diagnose by histopathological methods, whereas immunohistochemistry can provide a relatively correct diagnosis [18]. In this case, immunohistochemical staining of various elements was of assistance.…”