Primary rectal lymphoma: A case report and literature review

Jiang, Chunhui; Gu, Lei; Luo, Meng; Xu, Qing; Zhou, Hong

doi:10.3892/ol.2015.3164

Cited by 6 publications

(3 citation statements)

References 8 publications

(4 reference statements)

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“…Involvement of the colon is rare (10–20%), with the cecum being the segment most commonly affected. Primary rectal lymphoma is the rarest location of lymphomas, accounting for 0.05% of all primary rectal malignancies [ 8 ].…”

Section: Discussion/conclusionmentioning

confidence: 99%

Primary Diffuse Large B-Cell Lymphoma of the Rectum in a Non-Immunosuppressed Patient with Ulcerative Colitis

Saraiva¹,

Bernardo

Costa

et al. 2022

GE Port J Gastroenterol

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Introduction: The incidence of primary colorectal lymphoma in the gastrointestinal tract is very low, the rectum being infrequently affected. The development of this entity in inflammatory bowel disease patients usually occurs in a context of immunosuppression-based therapy, with only a few case reports describing its development in patients presenting no known risk factors. Moreover, the clinical presentation of primary colorectal lymphomas may be difficult to distinguish from an acute flare of ulcerative colitis (UC). Case Presentation: We present a case of non-Hodgkin lymphoma of the rectum in a 42-year-old male with a 7-year history of UC and no previous exposure to immunomodulatory agents. He presented with a history of mucous diarrhoea, tenesmus, proctalgia and weight loss, refractory to optimized therapy. A lower gastrointestinal endoscopy was performed revealing a circumferential ulcerated lesion of the rectum, from which histopathological analysis established the diagnosis of a non-Hodgkin diffuse large B-cell lymphoma (DLBCL). Discussion/Conclusion: The present case suggests the existence of alternative mechanisms for the development of DLBCL in UC patients. The clinical presentation mimicking an acute flare of UC posed a diagnostic challenge, highlighting the complexity behind the management of UC patients.

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Section: Discussion/conclusionmentioning

confidence: 99%

Primary Diffuse Large B-Cell Lymphoma of the Rectum in a Non-Immunosuppressed Patient with Ulcerative Colitis

Saraiva¹,

Bernardo

Costa

et al. 2022

GE Port J Gastroenterol

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“…In contrast to adenocarcinoma, GI lymphoma develops pathologically from the lymphoid follicle at the submucosal layer, which leads to the spread of disease mainly within this layer, making it difficult to diagnosis by a mucosal biopsy. 11 An abdominal CT examination may show a degree of infiltration by the tumor or enlargement of regional lymph node. 12 Actinomycosis is a chronic suppurative granulomatous disease caused by an anaerobic or microaerobic strain that normally is found in the mouth, colon, and female genitals; the most common strain is Actinomyces israelii.…”

Section: Discussionmentioning

confidence: 99%

Colonic Diffuse Large B-cell Lymphoma Hidden in Actinomycosis

Lee

Nam

Lee

et al. 2019

Korean J Gastroenterol

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Actinomycosis can mask malignant diseases. This paper reports a case of colonic diffuse large B-cell lymphoma (DLBCL), which was misdiagnosed as abdominal actinomycosis. A 76-year-old woman presented with right flank pain and weight loss. Abdominal CT and colonoscopy revealed a huge ascending colon mass. Despite the initial impression of a malignancy, a colonoscopic biopsy revealed no malignant cells, but sulfur granules and a filamentous organism suggesting actinomycosis. Intravenous penicillin G was administered under the impression of abdominal actinomycosis but her condition deteriorated rapidly. Follow up CT showed markedly increased colon mass and new multiple nodular lesions around the ascending colon. Sono-guided percutaneous biopsy of the nodular lesion was performed. The pathological result was DLBCL. The patient was scheduled to undergo chemotherapy but the patient expired due to cancer progression. The diagnosis of gastrointestinal infiltrating tumors is often difficult because a superficial biopsy usually does not provide a confirmative diagnosis. This case highlights the difficulty in making a correct diagnosis of lymphoma due to the concomitant actinomycosis. Malignant conditions must be considered in cases of actinomycosis with no response to antimicrobial therapy. (Korean J Gastroenterol 2019;74:46-50)

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“…Despite its rarity, the incidence of colonic GI non-Hodgkin lymphoma has increased nearly 5-fold since the 1990s, yet there is little consensus regarding its staging, treatment, and follow-up. 8 , 11 The majority of recently published works regarding colorectal MALT lymphoma originate from Japan, Korea, and China; there is little known about the current state of the disease and its management in the United States. 5 …”

Section: Discussionmentioning

confidence: 99%

Mucosa-Associated Lymphoid Tissue Lymphoma of the Sigmoid Colon Discovered on Routine Screening Colonoscopy in Patient with Hepatitis C and Helicobacter pylori Infection

Bhuta

Bromberg

Bains

et al. 2016

ACG Case Reports Journal

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Mucosa-associated lymphoid tissue (MALT) lymphoma is predominantly found in the stomach. Rarely, it is found in the proximal colon and even less so in the sigmoid colon. We present a rare case of primary sigmoid colon MALT lymphoma in a patient with concomitant Helicobacter pylori and hepatitis C infection. We also review current imaging, staging, and therapeutic modalities. To our knowledge, this is the first sigmoid colon MALT lymphoma reported in the United States.

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Primary rectal lymphoma: A case report and literature review

Cited by 6 publications

References 8 publications

Primary Diffuse Large B-Cell Lymphoma of the Rectum in a Non-Immunosuppressed Patient with Ulcerative Colitis

Primary Diffuse Large B-Cell Lymphoma of the Rectum in a Non-Immunosuppressed Patient with Ulcerative Colitis

Colonic Diffuse Large B-cell Lymphoma Hidden in Actinomycosis

Mucosa-Associated Lymphoid Tissue Lymphoma of the Sigmoid Colon Discovered on Routine Screening Colonoscopy in Patient with Hepatitis C and Helicobacter pylori Infection

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