Primary pulmonary T-cell lymphoma with lung adenocarcinoma: a case report

Abstract

Background Primary pulmonary T-cell lymphoma is an extremely rare disease that is characterized by neoplastic proliferation of T-cell lymphocytes in the lung. Case presentation An 88-year-old Japanese woman was admitted to our hospital because of dyspnea. She was treated with antibiotics for chest x-ray findings of consolidation in the upper and middle lobes of the right lung. However, her condition worsened and progressed to respiratory failure, which led to death 14 days after admission. Autopsy of the lungs revealed both T-cell lymphoma and adenocarcinoma. Conclusions Our patient had a rare case of primary pulmonary T-cell lymphoma with primary lung adenocarcinoma. Further evidence and accumulation of case reports are required to clarify the pathophysiology of primary pulmonary T-cell lymphoma.

Primary pulmonary T-cell lymphoma mimicking asthma and community-acquired pneumonia: a rare case report

“…The most common PPTL presentation is multiple nodules distributed in both lungs, accounting for 53.3% of cases [3] . Takahara et al suggests that the non-specific radiologic characteristics observed in PPTL cases are due to atypical lymphoid cells that can infiltrate the lungs through three different pathways: infiltration into lymphatic vessels, direct invasion, or hematogenous metastasis [8] . CT angiogram sign has been described as a potential clue for mucosa-associated lymphoid tissue pulmonary lymphoma originating from B-cell lymphocytes [9] .…”